Hs03006167_cn

• Gene Symbol: POLR1A
• Assay Reference Genome Location: Chr.2:86031477 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 25885
• Gene Name: RNA polymerase I subunit A
• Gene Aliases: A190, AFDCIN, RPA1, RPA194, RPO1-4, RPO14
• Location: Chr.2:86026328-86106155 on Build GRCh38
• Assay Gene Location: Within Exon 30

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR1A	NM_015425.4	30	4810	NP_056240.2
	AK025568.1	7	989	BAB15171.1
	AK294447.1	19	3039
	AK302458.1	30	4535
	AK304131.1	17	2787
	BC017115.1	7	995
	BC117173.1	30	4463
	BC126303.1	30	4463
	BC143345.1	30	4463
	U33460.1	30	4504	AAC99959.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2751903	Chr.2:86026419 - 86278330 on Build GRCh38	Gain	MRPL35 SNORD94 REEP1 IMMT MIR4779 POLR1A PTCD3
esv32617	Chr.2:86029518 - 86033162 on Build GRCh38	Loss	POLR1A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
positive regulation of gene expression, epigenetic

Function(s)

RNA polymerase I activity
DNA binding
protein binding
zinc ion binding