Hs03020122_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137175135 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Overlaps Intron 12 - Exon 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	LOC101930307 CYSRT1 RNF224 TPRN TMEM203 SLC34A3 MIR3621 UAP1L1 GRIN1 LRRC26 TMEM210 DPP7 MAN1B1-AS1 SSNA1 MAN1B1 NDOR1 ANAPC2 RNF208
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	STPG3 CYSRT1 RNF224 TUBB4B TPRN TMEM203 SLC34A3 TOR4A NRARP NELFB C9orf173-AS1 SSNA1 NDOR1 FAM166A ANAPC2 EXD3 RNF208
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TUBB4B TOR4A GRIN1 NRARP LRRC26 NELFB SSNA1 CCDC183-AS1 FAM166A ENTPD8 ANAPC2 NPDC1 CCDC183 LOC101930307 ABCA2 FBXW5 CLIC3 TMEM203 SLC34A3 ENTPD2 MIR7114 PNPLA7 C8G TRAF2 EDF1 C9orf139 RABL6 C9orf173-AS1 NDOR1 PTGDS EXD3 LCNL1 CYSRT1 SAPCD2 RNF224 TPRN PHPT1 NOXA1 DPP7 MAN1B1-AS1 MAN1B1 MIR4292 C9orf142 FUT7 RNF208 STPG3 MIR4479 MAMDC4 MIR3621 UAP1L1 LCN12 TMEM210 PRR31 NSMF C9orf172
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	STPG3 CYSRT1 RNF224 TUBB4B TPRN TMEM203 SLC34A3 TOR4A MIR3621 GRIN1 NRARP LRRC26 TMEM210 NELFB C9orf173-AS1 SSNA1 NDOR1 FAM166A ANAPC2 EXD3 RNF208
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	LOC101930307 SAPCD2 ENTPD2 MIR3621 UAP1L1 GRIN1 LRRC26 TMEM210 DPP7 C9orf139 MAN1B1-AS1 SSNA1 MAN1B1 ANAPC2 FUT7 NPDC1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	STPG3 CYSRT1 RNF224 TUBB4B TPRN TMEM203 NOXA1 SLC34A3 TOR4A MIR3621 GRIN1 NRARP LRRC26 TMEM210 NELFB C9orf173-AS1 SSNA1 NDOR1 FAM166A ENTPD8 ANAPC2 EXD3 RNF208
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	AGPAT2 FAM69B TUBB4B TOR4A GRIN1 NRARP LRRC26 NELFB SSNA1 CCDC183-AS1 FAM166A ANAPC2 NPDC1 SNORA17A CCDC183 LOC101930307 ABCA2 LCN15 FBXW5 CLIC3 TMEM203 SLC34A3 ENTPD2 MIR6722 LCN8 HSPC324 LCN10 C8G TRAF2 EDF1 C9orf139 RABL6 C9orf173-AS1 NDOR1 PTGDS EXD3 LCNL1 CYSRT1 SAPCD2 RNF224 TPRN PHPT1 LOC100128593 DPP7 MAN1B1-AS1 MIR126 MAN1B1 TMEM141 MIR4292 C9orf142 FUT7 RNF208 EGFL7 STPG3 LCN6 MIR4479 LINC01451 MAMDC4 MIR3621 UAP1L1 LCN12 TMEM210 PRR31 SNHG7 C9orf172 SNORA17B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity