Hs03051589_cn

• Gene Symbol: LOC339059
• Assay Reference Genome Location: Chr.16:88742940 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 339059
• Gene Name: uncharacterized LOC339059
• Gene Aliases: -
• Location: Chr.16:88742767-88745748 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC339059	NR_120387.1	1	174
	AK097767.1	1	174	BAC05165.1
	BC111769.1	1	120	AAI11770.1

Target Gene Details

• Entrez Gene ID: 9780
• Gene Name: piezo type mechanosensitive ion channel component 1
• Gene Aliases: DHS, FAM38A, LMPH3, Mib
• Location: Chr.16:88715338-88785220 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIEZO1	NM_001142864.3			NP_001136336.2
	HY165228.1
	KC602455.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CTU2 LOC107987238 APRT TRAPPC2L SLC22A31 LOC339059 CBFA2T3 GALNS LOC100129697 CDT1 LOC105371409 PIEZO1 MIR4722 ZNF778 CDH15 LOC400558 PABPN1L ACSF3 LOC101927793 LINC00304 LOC100289580
nsv471113	Chr.16:88650665 - 88764428 on Build GRCh38	Loss	SNAI3 MVD CTU2 CYBA PIEZO1 MIR4722 LOC339059 SNAI3-AS1 RNF166 LOC100289580
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	SNAI3 GALNS CTU2 CDT1 LOC107987238 PIEZO1 APRT MIR4722 LOC339059 SNAI3-AS1 RNF166 LOC100289580
nsv517643	Chr.16:88713767 - 88756339 on Build GRCh38	Loss	CTU2 PIEZO1 MIR4722 LOC339059 LOC100289580
nsv833327	Chr.16:88667431 - 88757621 on Build GRCh38	Loss	SNAI3 CTU2 PIEZO1 MIR4722 LOC339059 SNAI3-AS1 RNF166 LOC100289580
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC107987238 APRT LOC105371414 TRAPPC2L SLC22A31 LOC100287036 LOC339059 CBFA2T3 GALNS ANKRD11 LOC100129697 CDT1 LOC105371409 PIEZO1 ZNF778 CDH15 LOC400558 PABPN1L ACSF3 LOC101927793 LINC00304 LOC100289580
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	TCF25 SPATA2L CYBA RPL13 LOC107987238 PRDM7 DEF8 SNAI3 GALNS DBNDD1 MVD CENPBD1 ZNF778 CDH15 LOC400558 FANCA CPNE7 GAS8 CDK10 APRT LOC105371414 TRAPPC2L SLC22A31 SNAI3-AS1 SPIRE2 TUBB3 ANKRD11 FAM157C ZNF276 PABPN1L LINC00304 LOC101927817 VPS9D1-AS1 GAS8-AS1 CBFA2T3 SNORD68 LOC100129697 LOC105371409 PIEZO1 AFG3L1P IL17C MIR4722 ACSF3 TUBB8P7 VPS9D1 CHMP1A CTU2 LOC107984817 SPATA33 LOC100287036 DPEP1 LOC339059 URAHP SPG7 CDT1 MC1R LOC105371419 RNF166 LOC101927793 LOC100289580
nsv1927	Chr.16:88712585 - 88743583 on Build GRCh38	Insertion	CTU2 PIEZO1 MIR4722 LOC339059 LOC100289580
nsv471114	Chr.16:88688461 - 88756339 on Build GRCh38	Gain	CTU2 PIEZO1 MIR4722 LOC339059 RNF166 LOC100289580
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	ZC3H18-AS1 CTU2 CYBA ZNF469 LOC107984862 LOC339059 SNAI3-AS1 ZC3H18 MIR5189 SNAI3 MVD PIEZO1 IL17C MIR4722 ZFPM1 RNF166 LOC100289580
nsv1160442	Chr.16:88708161 - 88778524 on Build GRCh38	Deletion	CTU2 PIEZO1 MIR4722 LOC339059 LOC100289580
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	CTU2 LOC107987238 APRT TRAPPC2L LOC339059 CBFA2T3 GALNS LOC100129697 CDT1 LOC105371409 PIEZO1 MIR4722 PABPN1L LOC101927793 LOC100289580
nsv573675	Chr.16:88740797 - 88743485 on Build GRCh38	Loss	PIEZO1 LOC339059 LOC100289580

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cation transport
positive regulation of integrin activation
positive regulation of cell-cell adhesion mediated by integrin
cation transmembrane transport

Function(s)

cation channel activity
mechanically-gated ion channel activity