Hs03064483_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137183158 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3	6	1326	NP_037498.1
	AB037827.1	4	502	BAA92644.1
	AF191337.1	6	1253	AAF05751.1
	AK294601.1	6	1281
	BC001579.1	4	518	AAH01579.1
	BC009487.2	2	117	AAH09487.2
	BC032503.1	6	1258	AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	NDOR1 SSNA1 UAP1L1 GRIN1 TMEM210 RNF208 MAN1B1-AS1 TPRN TMEM203 SLC34A3 LRRC26 RNF224 MAN1B1 DPP7 MIR3621 ANAPC2 LOC101930307 CYSRT1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	NDOR1 SSNA1 TUBB4B C9orf173-AS1 NRARP RNF208 TPRN TMEM203 SLC34A3 RNF224 ANAPC2 STPG3 FAM166A NELFB TOR4A EXD3 CYSRT1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NPDC1 TUBB4B ENTPD8 SLC34A3 STPG3 ABCA2 FAM166A MIR4292 PRR31 NSMF EXD3 C8G ENTPD2 TMEM210 EDF1 NRARP RABL6 MAN1B1 DPP7 MIR3621 ANAPC2 C9orf142 FBXW5 CCDC183 CYSRT1 MIR4479 NDOR1 SSNA1 NOXA1 PTGDS C9orf173-AS1 CLIC3 C9orf172 PNPLA7 MAN1B1-AS1 LCN12 TPRN TMEM203 LRRC26 LOC101930307 LCNL1 NELFB FUT7 TOR4A PHPT1 CCDC183-AS1 MIR7114 UAP1L1 GRIN1 SAPCD2 RNF208 MAMDC4 RNF224 C9orf139 TRAF2
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	NDOR1 SSNA1 TUBB4B C9orf173-AS1 GRIN1 TMEM210 NRARP RNF208 TPRN TMEM203 SLC34A3 LRRC26 RNF224 MIR3621 ANAPC2 STPG3 FAM166A NELFB TOR4A EXD3 CYSRT1
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	SSNA1 NPDC1 ENTPD2 UAP1L1 GRIN1 TMEM210 SAPCD2 MAN1B1-AS1 LRRC26 MAN1B1 DPP7 MIR3621 ANAPC2 LOC101930307 FUT7 C9orf139
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NDOR1 SSNA1 NOXA1 TUBB4B C9orf173-AS1 GRIN1 TMEM210 ENTPD8 NRARP RNF208 TPRN TMEM203 SLC34A3 LRRC26 RNF224 MIR3621 ANAPC2 STPG3 FAM166A NELFB TOR4A EXD3 CYSRT1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	NPDC1 TUBB4B HSPC324 SLC34A3 STPG3 ABCA2 FAM166A MIR4292 PRR31 LCN8 EXD3 C8G ENTPD2 MIR126 TMEM141 TMEM210 EDF1 NRARP RABL6 EGFL7 MAN1B1 DPP7 MIR3621 ANAPC2 C9orf142 SNHG7 SNORA17B FBXW5 CCDC183 CYSRT1 MIR4479 NDOR1 SSNA1 PTGDS C9orf173-AS1 CLIC3 C9orf172 MAN1B1-AS1 LCN12 TPRN TMEM203 LRRC26 LOC101930307 LCNL1 NELFB FUT7 AGPAT2 SNORA17A MIR6722 TOR4A PHPT1 CCDC183-AS1 LCN6 UAP1L1 LOC100128593 GRIN1 SAPCD2 RNF208 LINC01451 MAMDC4 LCN10 FAM69B RNF224 LCN15 C9orf139 TRAF2

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity