Hs03072533_cn

• Gene Symbol: HSD17B11
• Assay Reference Genome Location: Chr.4:87336997 on build GRCh38
• Cytoband: 4q22.1

Target Gene Details

• Entrez Gene ID: 51170
• Gene Name: hydroxysteroid 17-beta dehydrogenase 11
• Gene Aliases: 17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2
• Location: Chr.4:87336522-87391303 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
HSD17B11	NM_016245.4	7	1415	NP_057329.3
	AF126780.1	7	1370	AAF06939.1
	AF273056.1	7	1268	AAM44459.1
	AK075348.1	7	1299	BAC11560.1
	AY358553.1	7	1282	AAQ88917.1
	BC008650.1	7	1305	AAH08650.1
	BC014327.1	7	1281	AAH14327.1
	BC016367.1	7	1312	AAH16367.1
	BC021673.1	7	1286	AAH21673.1
	BC036001.1	7	1306	AAH36001.1
	BM976691.1	1	489
	CA775960.1	1	385
	CB163647.1	1	90

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1004518	Chr.4:87297321 - 87433251 on Build GRCh38	Gain	NUDT9 HSD17B11 MIR5705 HSD17B13
esv3601271	Chr.4:87289406 - 87409657 on Build GRCh38	Loss	HSD17B11 MIR5705 HSD17B13
nsv4412	Chr.4:87316661 - 87362216 on Build GRCh38	Deletion	HSD17B11 HSD17B13
nsv1002789	Chr.4:87318188 - 87685333 on Build GRCh38	Loss	NUDT9 SPARCL1 HSD17B11 DMP1 HSD17B13 DSPP

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

steroid biosynthetic process
estrogen biosynthetic process
androgen catabolic process
oxidation-reduction process

Function(s)

estradiol 17-beta-dehydrogenase activity
steroid dehydrogenase activity