Hs03250172_cn

• Gene Symbol: NEURL1B
• Assay Reference Genome Location: Chr.5:172656979 on build GRCh38
• Cytoband: 5q35.1

Target Gene Details

• Entrez Gene ID: 54492
• Gene Name: neuralized E3 ubiquitin protein ligase 1B
• Gene Aliases: NEURL3, hNeur2, neur2
• Location: Chr.5:172641266-172691540 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NEURL1B	NM_001142651.2			NP_001136123.1
	NM_001308177.1			NP_001295106.1
	NM_001308178.1			NP_001295107.1
	GQ414757.1
	GQ414758.1
	GQ414759.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv208e55	Chr.5:172656276 - 172752581 on Build GRCh38	Gain	LOC100130394 MIR5003 NEURL1B
nsv600287	Chr.5:172627918 - 172694311 on Build GRCh38	Loss	LOC100130394 MIR5003 NEURL1B
esv34432	Chr.5:172591201 - 172752581 on Build GRCh38	Gain	LOC100130394 MIR5003 NEURL1B
dgv5831n100	Chr.5:172645828 - 172753954 on Build GRCh38	Gain	LOC100130394 MIR5003 NEURL1B
esv2759393	Chr.5:172554329 - 172788409 on Build GRCh38	Gain	LOC100130394 MIR5003 LOC101928093 NEURL1B DUSP1
esv2763518	Chr.5:172653533 - 172735933 on Build GRCh38	Gain	LOC100130394 MIR5003 NEURL1B
nsv523045	Chr.5:172652886 - 172728004 on Build GRCh38	Gain	LOC100130394 MIR5003 NEURL1B

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

Notch signaling pathway
protein ubiquitination
ubiquitin-dependent endocytosis

Function(s)

protein binding
zinc ion binding
ligase activity