Hs03436797_cn

• Gene Symbol: LIMS2
• Assay Reference Genome Location: Chr.2:127645613 on build GRCh38
• Cytoband: 2q14.3

Target Gene Details

• Entrez Gene ID: 55679
• Gene Name: LIM zinc finger domain containing 2
• Gene Aliases: LGMD2W, PINCH-2, PINCH2
• Location: Chr.2:127638421-127681786 on Build GRCh38
• Assay Gene Location: Within Intron 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LIMS2	NM_001136037.2			NP_001129509.2
	NM_001161403.1			NP_001154875.1
	NM_001161404.1			NP_001154876.1
	NM_001256542.1			NP_001243471.1
	NM_017980.4			NP_060450.2
	XM_005263710.2			XP_005263767.1
	XM_006712627.3			XP_006712690.1
	XM_011511453.1			XP_011509755.1
	AF484961.1			AAM97589.1
	AF520987.1			AAM77350.1
	AF527764.1			AAQ09011.1
	AF527765.1			AAQ09012.1
	AF527766.1			AAQ09013.1
	AF527767.1			AAQ09014.1
	AF527770.1			AAQ09017.1
	AK000906.1			BAA91419.1
	AK022470.1			BAB14047.1
	AK055363.1
	AK091652.1
	AK094954.1
	AK095790.1
	AK123014.1
	AK297645.1
	BC065816.1			AAH65816.1
	BX458594.2
	DA848179.1
	DC356496.1
	DR006887.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517532	Chr.2:127630362 - 127647285 on Build GRCh38	Loss	MYO7B LIMS2 GPR17
dgv4069n100	Chr.2:127537744 - 127722066 on Build GRCh38	Gain	SFT2D3 WDR33 MYO7B LIMS2 LOC105373609 GPR17
nsv508864	Chr.2:127585891 - 127684658 on Build GRCh38	Insertion	MYO7B LIMS2 GPR17
nsv953155	Chr.2:127617926 - 127665326 on Build GRCh38	Deletion	MYO7B LIMS2 GPR17
nsv518085	Chr.2:127576838 - 127647285 on Build GRCh38	Loss	MYO7B LIMS2 GPR17
nsv470482	Chr.2:127593233 - 127707973 on Build GRCh38	Loss	SFT2D3 WDR33 MYO7B LIMS2 GPR17
nsv583038	Chr.2:127641265 - 127718910 on Build GRCh38	Loss	SFT2D3 WDR33 LIMS2 GPR17

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

cell junction protein

Gene Ontology Categories:

Process(es)

single organismal cell-cell adhesion
cell junction assembly
negative regulation of apoptotic process
cell-cell junction organization
negative regulation of neural precursor cell proliferation
negative regulation of hepatocyte proliferation
positive regulation of integrin-mediated signaling pathway

Function(s)

zinc ion binding