Hs03510221_cn

• Gene Symbol: GRXCR1
• Assay Reference Genome Location: Chr.4:42903084 on build GRCh38
• Cytoband: 4p13

Target Gene Details

• Entrez Gene ID: 389207
• Gene Name: glutaredoxin and cysteine rich domain containing 1
• Gene Aliases: DFNB25, PPP1R88
• Location: Chr.4:42893266-43030658 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRXCR1	NM_001080476.2			NP_001073945.1
	DT932651.1
	DY654338.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv872n67	Chr.4:42903094 - 42903841 on Build GRCh38	Loss	GRXCR1
esv2727494	Chr.4:42903128 - 42903831 on Build GRCh38	Deletion	GRXCR1
esv3563781	Chr.4:42903092 - 42903896 on Build GRCh38	Deletion	GRXCR1
esv7471	Chr.4:42902957 - 42904056 on Build GRCh38	Loss	GRXCR1
esv5262	Chr.4:42903115 - 42903916 on Build GRCh38	Loss	GRXCR1

More Information

Additional Information:

For this assay, SNP(s) [rs143492369] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

sensory perception of sound
negative regulation of phosphatase activity
cell redox homeostasis
oxidation-reduction process
vestibular receptor cell development
inner ear receptor cell development
inner ear receptor stereocilium organization

Function(s)

molecular_function
electron carrier activity
protein disulfide oxidoreductase activity