Hs03542651_cn

• Gene Symbol: GRK6
• Assay Reference Genome Location: Chr.5:177426571 on build GRCh38
• Cytoband: 5q35.3

Target Gene Details

• Entrez Gene ID: 2870
• Gene Name: G protein-coupled receptor kinase 6
• Gene Aliases: GPRK6
• Location: Chr.5:177426496-177442849 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRK6	XM_006714859.2	1	76	XP_006714922.1
	XM_011534537.2			XP_011532839.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv471057	Chr.5:177310308 - 177469411 on Build GRCh38	Loss	MXD3 LMAN2 PRR7 PRR7-AS1 SLC34A1 F12 PFN3 RGS14 GRK6 DBN1
nsv600364	Chr.5:177299634 - 177432847 on Build GRCh38	Loss	MXD3 LMAN2 SLC34A1 F12 PFN3 RAB24 PRELID1 NSD1 RGS14 GRK6
dgv10184n54	Chr.5:177357511 - 177469411 on Build GRCh38	Loss	PRR7 PRR7-AS1 SLC34A1 F12 PFN3 RGS14 GRK6 DBN1
nsv1161313	Chr.5:177356552 - 177463415 on Build GRCh38	Duplication	PRR7 PRR7-AS1 SLC34A1 F12 PFN3 RGS14 GRK6 DBN1
nsv1161311	Chr.5:177305104 - 177546474 on Build GRCh38	Duplication	MXD3 LMAN2 PFN3 PRELID1 GRK6 DBN1 FAM193B PDLIM7 PRR7 PRR7-AS1 SLC34A1 F12 DDX41 DOK3 RGS14

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

desensitization of G-protein coupled receptor protein signaling pathway
protein phosphorylation
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of anion channel activity
Wnt signaling pathway

Function(s)

G-protein coupled receptor kinase activity
protein binding
ATP binding
beta-adrenergic receptor kinase activity