Hs03629793_cn

• Gene Symbol: POR
• Assay Reference Genome Location: Chr.7:75960637 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 5447
• Gene Name: cytochrome p450 oxidoreductase
• Gene Aliases: CPR, CYPOR, P450R
• Location: Chr.7:75915102-75986855 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POR	NM_000941.2			NP_000932.3
	AB051763.1			BAB18572.1
	AB209874.1			BAD93111.1
	AF258341.1			AAG09798.1
	AK129978.1
	AK290529.1
	AK312543.1
	BC034277.1			AAH34277.1
	BP244929.1
	BX648619.1			CAH56151.1
	DA701694.1
	S90469.1			AAB21814.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428173	Chr.7:75934531 - 76173362 on Build GRCh38	Gain	LOC107986711 GTF2IP7 SNORA14A TMEM120A STYXL1 POR MDH2
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	TRIM73 PMS2P2 SNORA14A GTF2IRD2B STAG3L1 LOC105375355 SPDYE5 MIR4651 ZP3 YWHAG LOC441259 TMEM120A RHBDD2 STYXL1 CCL24 FDPSP2 POMZP3 SRRM3 GTF2IP1 NSUN5P1 HSPB1 NCF1C POM121C SSC4D CCL26 MDH2 PMS2P10 LOC100133091 DTX2 LOC107986711 GTF2IP7 SPDYE16 LOC541473 HIP1 PMS2P3 POR
esv3613742	Chr.7:75912784 - 76036530 on Build GRCh38	Loss	MIR4651 SNORA14A TMEM120A STYXL1 POR
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SNORA14A LOC105375355 SPDYE5 MIR4651 ZP3 YWHAG TMEM120A RHBDD2 STYXL1 CCL24 FDPSP2 POMZP3 SRRM3 HSPB1 POM121C SSC4D CCL26 MDH2 LOC100133091 DTX2 LOC107986711 GTF2IP7 SPDYE16 HIP1 PMS2P3 POR

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

regulation of growth plate cartilage chondrocyte proliferation
xenobiotic metabolic process
response to nutrient
carnitine metabolic process
flavonoid metabolic process
internal peptidyl-lysine acetylation
fatty acid oxidation
positive regulation of chondrocyte differentiation
positive regulation of monooxygenase activity
response to drug
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
nitrate catabolic process
positive regulation of cholesterol biosynthetic process
positive regulation of smoothened signaling pathway
nitric oxide catabolic process
oxidation-reduction process
negative regulation of lipase activity
demethylation
cellular response to follicle-stimulating hormone stimulus
cellular response to peptide hormone stimulus
positive regulation of steroid hormone biosynthetic process
cellular organofluorine metabolic process

Function(s)

NADPH-hemoprotein reductase activity
cytochrome-b5 reductase activity, acting on NAD(P)H
protein binding
nitric oxide dioxygenase activity
electron carrier activity
FMN binding
hydrolase activity
enzyme binding
[methionine synthase] reductase activity
iron-cytochrome-c reductase activity
flavin adenine dinucleotide binding
NADP binding