Hs03637084_cn

• Gene Symbol: POR
• Assay Reference Genome Location: Chr.7:75920678 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 5447
• Gene Name: cytochrome p450 oxidoreductase
• Gene Aliases: CPR, CYPOR, P450R
• Location: Chr.7:75915102-75986855 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POR	NM_000941.2			NP_000932.3
	AK129978.1
	AK290529.1
	AK312543.1
	BP244929.1
	BX648619.1			CAH56151.1
	DA701694.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	POM121C PMS2P2 LOC541473 TMEM120A STAG3L1 LOC105375355 SRRM3 POR SPDYE5 FDPSP2 SSC4D LOC107986711 RHBDD2 POMZP3 NCF1C NSUN5P1 MIR4651 DTX2 LOC100133091 STYXL1 SNORA14A GTF2IP7 CCL24 GTF2IP1 SPDYE16 HSPB1 HIP1 ZP3 YWHAG GTF2IRD2B PMS2P10 PMS2P3 LOC441259 MDH2 TRIM73 CCL26
esv3613742	Chr.7:75912784 - 76036530 on Build GRCh38	Loss	MIR4651 STYXL1 TMEM120A SNORA14A POR
esv3613743	Chr.7:75917905 - 75929949 on Build GRCh38	Loss	POR
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	POM121C TMEM120A LOC105375355 SRRM3 POR SPDYE5 FDPSP2 SSC4D LOC107986711 RHBDD2 POMZP3 MIR4651 DTX2 LOC100133091 STYXL1 SNORA14A GTF2IP7 CCL24 SPDYE16 HSPB1 HIP1 ZP3 YWHAG PMS2P3 MDH2 CCL26

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

regulation of growth plate cartilage chondrocyte proliferation
xenobiotic metabolic process
response to nutrient
carnitine metabolic process
flavonoid metabolic process
internal peptidyl-lysine acetylation
fatty acid oxidation
positive regulation of chondrocyte differentiation
positive regulation of monooxygenase activity
response to drug
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
nitrate catabolic process
positive regulation of cholesterol biosynthetic process
positive regulation of smoothened signaling pathway
nitric oxide catabolic process
oxidation-reduction process
negative regulation of lipase activity
demethylation
cellular response to follicle-stimulating hormone stimulus
cellular response to peptide hormone stimulus
positive regulation of steroid hormone biosynthetic process
cellular organofluorine metabolic process

Function(s)

NADPH-hemoprotein reductase activity
cytochrome-b5 reductase activity, acting on NAD(P)H
protein binding
nitric oxide dioxygenase activity
electron carrier activity
FMN binding
hydrolase activity
enzyme binding
[methionine synthase] reductase activity
iron-cytochrome-c reductase activity
flavin adenine dinucleotide binding
NADP binding