Hs03639665_cn

• Gene Symbol: SRPK2
• Assay Reference Genome Location: Chr.7:105115309 on build GRCh38
• Cytoband: 7q22.3

Target Gene Details

• Entrez Gene ID: 6733
• Gene Name: SRSF protein kinase 2
• Gene Aliases: SFRSK2
• Location: Chr.7:105110708-105399366 on Build GRCh38
• Assay Gene Location: Within Exon 22

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SRPK2	XM_017012560.1	17	4827	XP_016868049.1
	XM_017012561.1	16	4677	XP_016868050.1
	XM_017012563.1	17	5012	XP_016868052.1
	AY354201.1			AAQ63886.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv237e55	Chr.7:105097165 - 105512795 on Build GRCh38	Gain	PUS7 SRPK2 KMT2E
nsv608068	Chr.7:104981955 - 105117036 on Build GRCh38	Loss	KMT2E-AS1 SRPK2 LOC101927902 LINC01004 KMT2E
nsv436902	Chr.7:104802439 - 105205347 on Build GRCh38	Insertion	KMT2E-AS1 SRPK2 LOC101927902 LHFPL3-AS2 LHFPL3-AS1 LINC01004 KMT2E LHFPL3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

spliceosomal complex assembly
angiogenesis
protein phosphorylation
positive regulation of cell proliferation
RNA splicing
positive regulation of gene expression
cell differentiation
nuclear speck organization
intracellular signal transduction
positive regulation of neuron apoptotic process
positive regulation of viral genome replication
negative regulation of viral genome replication
innate immune response
positive regulation of cell cycle
regulation of mRNA splicing, via spliceosome

Function(s)

magnesium ion binding
protein serine/threonine kinase activity
protein binding
ATP binding
poly(A) RNA binding
14-3-3 protein binding