Hs03640918_cn

• Gene Symbol: POR
• Assay Reference Genome Location: Chr.7:75959302 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 5447
• Gene Name: cytochrome p450 oxidoreductase
• Gene Aliases: CPR, CYPOR, P450R
• Location: Chr.7:75915102-75986855 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POR	NM_000941.2			NP_000932.3
	AB051763.1			BAB18572.1
	AB209874.1			BAD93111.1
	AF258341.1			AAG09798.1
	AK129978.1
	AK290529.1
	AK312543.1
	BC034277.1			AAH34277.1
	BP244929.1
	BX648619.1			CAH56151.1
	DA701694.1
	S90469.1			AAB21814.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428173	Chr.7:75934531 - 76173362 on Build GRCh38	Gain	GTF2IP7 LOC107986711 POR MDH2 TMEM120A SNORA14A STYXL1
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	HSPB1 LOC107986711 SPDYE16 STAG3L1 PMS2P10 ZP3 CCL26 CCL24 GTF2IP7 SSC4D YWHAG SPDYE5 NSUN5P1 GTF2IP1 PMS2P2 RHBDD2 DTX2 POR NCF1C GTF2IRD2B MDH2 LOC100133091 LOC105375355 MIR4651 SNORA14A STYXL1 POMZP3 FDPSP2 LOC541473 LOC441259 POM121C TRIM73 SRRM3 PMS2P3 TMEM120A HIP1
esv3613742	Chr.7:75912784 - 76036530 on Build GRCh38	Loss	POR TMEM120A MIR4651 SNORA14A STYXL1
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	HSPB1 LOC107986711 SPDYE16 ZP3 CCL26 CCL24 GTF2IP7 SSC4D YWHAG SPDYE5 RHBDD2 DTX2 POR MDH2 LOC100133091 LOC105375355 MIR4651 SNORA14A STYXL1 POMZP3 FDPSP2 POM121C SRRM3 PMS2P3 TMEM120A HIP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

regulation of growth plate cartilage chondrocyte proliferation
xenobiotic metabolic process
response to nutrient
carnitine metabolic process
flavonoid metabolic process
internal peptidyl-lysine acetylation
fatty acid oxidation
positive regulation of chondrocyte differentiation
positive regulation of monooxygenase activity
response to drug
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
nitrate catabolic process
positive regulation of cholesterol biosynthetic process
positive regulation of smoothened signaling pathway
nitric oxide catabolic process
oxidation-reduction process
negative regulation of lipase activity
demethylation
cellular response to follicle-stimulating hormone stimulus
cellular response to peptide hormone stimulus
positive regulation of steroid hormone biosynthetic process
cellular organofluorine metabolic process

Function(s)

NADPH-hemoprotein reductase activity
cytochrome-b5 reductase activity, acting on NAD(P)H
protein binding
nitric oxide dioxygenase activity
electron carrier activity
FMN binding
hydrolase activity
enzyme binding
[methionine synthase] reductase activity
iron-cytochrome-c reductase activity
flavin adenine dinucleotide binding
NADP binding