Hs03642909_cn

• Gene Symbol: POR
• Assay Reference Genome Location: Chr.7:75956682 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 5447
• Gene Name: cytochrome p450 oxidoreductase
• Gene Aliases: CPR, CYPOR, P450R
• Location: Chr.7:75915102-75986855 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POR	NM_000941.2			NP_000932.3
	AB051763.1			BAB18572.1
	AB209874.1			BAD93111.1
	AF258341.1			AAG09798.1
	AK129978.1
	AK290529.1
	AK312543.1
	BC034277.1			AAH34277.1
	BP244929.1
	BX648619.1			CAH56151.1
	DA701694.1
	S90469.1			AAB21814.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428173	Chr.7:75934531 - 76173362 on Build GRCh38	Gain	TMEM120A POR GTF2IP7 STYXL1 MDH2 LOC107986711 SNORA14A
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	SPDYE5 LOC105375355 PMS2P10 POMZP3 STAG3L1 NCF1C HIP1 POM121C YWHAG LOC541473 PMS2P2 STYXL1 SSC4D CCL24 TMEM120A LOC441259 FDPSP2 LOC100133091 DTX2 TRIM73 NSUN5P1 ZP3 CCL26 SPDYE16 LOC107986711 SNORA14A RHBDD2 GTF2IP1 POR GTF2IP7 PMS2P3 SRRM3 HSPB1 GTF2IRD2B MIR4651 MDH2
esv3613742	Chr.7:75912784 - 76036530 on Build GRCh38	Loss	TMEM120A POR STYXL1 MIR4651 SNORA14A
esv3613744	Chr.7:75937441 - 75957916 on Build GRCh38	Loss	POR SNORA14A
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SPDYE5 LOC105375355 POMZP3 HIP1 POM121C YWHAG STYXL1 SSC4D CCL24 TMEM120A FDPSP2 LOC100133091 DTX2 ZP3 CCL26 SPDYE16 LOC107986711 SNORA14A RHBDD2 POR GTF2IP7 PMS2P3 SRRM3 HSPB1 MIR4651 MDH2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxidoreductase

Gene Ontology Categories:

Process(es)

regulation of growth plate cartilage chondrocyte proliferation
xenobiotic metabolic process
response to nutrient
carnitine metabolic process
flavonoid metabolic process
internal peptidyl-lysine acetylation
fatty acid oxidation
positive regulation of chondrocyte differentiation
positive regulation of monooxygenase activity
response to drug
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
nitrate catabolic process
positive regulation of cholesterol biosynthetic process
positive regulation of smoothened signaling pathway
nitric oxide catabolic process
oxidation-reduction process
negative regulation of lipase activity
demethylation
cellular response to follicle-stimulating hormone stimulus
cellular response to peptide hormone stimulus
positive regulation of steroid hormone biosynthetic process
cellular organofluorine metabolic process

Function(s)

NADPH-hemoprotein reductase activity
cytochrome-b5 reductase activity, acting on NAD(P)H
protein binding
nitric oxide dioxygenase activity
electron carrier activity
FMN binding
hydrolase activity
enzyme binding
[methionine synthase] reductase activity
iron-cytochrome-c reductase activity
flavin adenine dinucleotide binding
NADP binding