Hs03660127_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143991171 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1	2	262
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1
	BM762447.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PARP10 GRINA PLEC
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	ADCK5 PPP1R16A SLC52A2 LRRC14 SHARPIN WDR97 BOP1 FBXL6 HSF1 MIR6849 GPT MIR6846 MAF1 MFSD3 CYHR1 HGH1 MIR7112 EXOSC4 SPATC1 CPSF1 MROH1 RECQL4 MIR6847 TONSL-AS1 SLC39A4 GRINA CYC1 PLEC MIR6893 OPLAH MIR6848 SCX LOC101928953 TMEM249 FOXH1 MIR939 MIR661 KIFC2 PARP10 LOC101928902 GPAA1 SCRT1 TONSL VPS28 MIR1234 SMPD5 DGAT1
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	ADCK5 PPP1R16A SLC52A2 LRRC14 SHARPIN WDR97 BOP1 FBXL6 HSF1 MIR6849 GPT MIR6846 MAF1 MFSD3 CYHR1 HGH1 MIR7112 EXOSC4 SPATC1 CPSF1 MROH1 RECQL4 MIR6847 TONSL-AS1 SLC39A4 GRINA CYC1 PLEC MIR6893 OPLAH MIR6848 SCX LOC101928953 TMEM249 FOXH1 MIR939 MIR661 KIFC2 PARP10 LOC101928902 GPAA1 SCRT1 TONSL VPS28 MIR1234 SMPD5 DGAT1
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	OPLAH SHARPIN WDR97 MIR6846 MAF1 PARP10 EXOSC4 SPATC1 GPAA1 MIR6847 GRINA SMPD5 CYC1 PLEC
dgv12431n54	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	OPLAH EPPK1 SHARPIN WDR97 MIR6846 MIR661 MAF1 PARP10 HGH1 EXOSC4 SPATC1 GPAA1 MROH1 MIR6847 GRINA SMPD5 CYC1 PLEC
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	OPLAH EPPK1 SHARPIN WDR97 MIR6846 MIR661 MAF1 PARP10 EXOSC4 SPATC1 GPAA1 MIR6847 GRINA SMPD5 CYC1 PLEC
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	MIR937 OPLAH EPPK1 NRBP2 MIR6846 MIR661 LOC642574 PARP10 MIR6845 SCRIB EXOSC4 SPATC1 MIR6847 GRINA PUF60 SMPD5 PLEC
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	MIR6846 MIR661 OPLAH PARP10 EXOSC4 SPATC1 GPAA1 MIR6847 GRINA SMPD5 CYC1 PLEC
dgv12433n54	Chr.8:143902404 - 144120626 on Build GRCh38	Gain	OPLAH SHARPIN WDR97 MIR6846 MIR661 MAF1 PARP10 EXOSC4 SPATC1 GPAA1 MIR6847 GRINA SMPD5 CYC1 PLEC
nsv612906	Chr.8:143917935 - 144090784 on Build GRCh38	Loss	MIR6846 MIR661 OPLAH PARP10 EXOSC4 SPATC1 GPAA1 MIR6847 GRINA SMPD5 PLEC

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding