Hs03660127_cn

• Gene Symbol: GRINA
• Assay Reference Genome Location: Chr.8:143991171 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 2907
• Gene Name: glutamate ionotropic receptor NMDA type subunit associated protein 1
• Gene Aliases: HNRGW, LFG1, NMDARA1, TMBIM3
• Location: Chr.8:143990058-143993415 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GRINA	NM_000837.1			NP_000828.1
	NM_001009184.1			NP_001009184.1
	AB097026.1			BAC77379.1
	AK127640.1	2	262
	AK294127.1
	BC041788.1			AAH41788.2
	BC084553.1			AAH84553.1
	BM762447.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv6445	Chr.8:143961415 - 143994522 on Build GRCh38	Insertion	PLEC GRINA PARP10
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	ADCK5 PPP1R16A HGH1 GPT SLC39A4 MIR6849 PARP10 RECQL4 LOC101928902 GPAA1 FOXH1 OPLAH MIR6893 MFSD3 CYHR1 TMEM249 TONSL SMPD5 EXOSC4 MIR1234 VPS28 DGAT1 WDR97 CYC1 SCX CPSF1 PLEC BOP1 MIR6847 MIR661 SHARPIN MIR7112 MIR6846 MAF1 MIR939 KIFC2 SPATC1 MIR6848 SLC52A2 MROH1 LOC101928953 HSF1 TONSL-AS1 FBXL6 SCRT1 GRINA LRRC14
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	ADCK5 PPP1R16A HGH1 GPT SLC39A4 MIR6849 PARP10 RECQL4 LOC101928902 GPAA1 FOXH1 OPLAH MIR6893 MFSD3 CYHR1 TMEM249 TONSL SMPD5 EXOSC4 MIR1234 VPS28 DGAT1 WDR97 CYC1 SCX CPSF1 PLEC BOP1 MIR6847 MIR661 SHARPIN MIR7112 MIR6846 MAF1 MIR939 KIFC2 SPATC1 MIR6848 SLC52A2 MROH1 LOC101928953 HSF1 TONSL-AS1 FBXL6 SCRT1 GRINA LRRC14
nsv612914	Chr.8:143972494 - 144120626 on Build GRCh38	Loss	WDR97 CYC1 PLEC MIR6847 SHARPIN MIR6846 MAF1 PARP10 SPATC1 GPAA1 OPLAH SMPD5 EXOSC4 GRINA
dgv906n27	Chr.8:143845100 - 144161320 on Build GRCh38	Loss	WDR97 CYC1 HGH1 PLEC MIR6847 MIR661 SHARPIN MIR6846 MAF1 PARP10 SPATC1 GPAA1 OPLAH MROH1 SMPD5 EPPK1 EXOSC4 GRINA
nsv950015	Chr.8:143866633 - 144125597 on Build GRCh38	Deletion	WDR97 CYC1 PLEC MIR6847 MIR661 SHARPIN MIR6846 MAF1 PARP10 SPATC1 GPAA1 OPLAH SMPD5 EPPK1 EXOSC4 GRINA
nsv1161815	Chr.8:143775169 - 144080674 on Build GRCh38	Deletion	PLEC MIR6847 MIR661 MIR937 MIR6846 PARP10 SCRIB SPATC1 MIR6845 OPLAH LOC642574 SMPD5 EPPK1 EXOSC4 GRINA NRBP2 PUF60
dgv12432n54	Chr.8:143902404 - 144007080 on Build GRCh38	Loss	PLEC MIR661 GRINA PARP10
nsv470250	Chr.8:143917934 - 144097007 on Build GRCh38	Gain	SPATC1 CYC1 GPAA1 OPLAH PLEC SMPD5 MIR6847 MIR661 EXOSC4 GRINA MIR6846 PARP10
nsv612907	Chr.8:143917935 - 144097007 on Build GRCh38	Gain+Loss	SPATC1 CYC1 GPAA1 OPLAH PLEC SMPD5 MIR6847 MIR661 EXOSC4 GRINA MIR6846 PARP10

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

endoplasmic reticulum calcium ion homeostasis
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Function(s)

ion channel binding