Hs03660637_cn

• Gene Symbol: LOC286059
• Assay Reference Genome Location: Chr.8:23068294 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 286059
• Gene Name: tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain pseudogene
• Gene Aliases: -
• Location: Chr.8:23068229-23083619 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC286059	NR_038873.1
	AK024295.1

Target Gene Details

• Entrez Gene ID: 8795
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Location: Chr.8:23020133-23069187 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF10B	NM_003842.4			NP_003833.4
	NM_147187.2			NP_671716.2
	NR_027140.1
	AB451272.1
	AB451399.1
	AF012535.1			AAB67103.1
	AF012628.1			AAB67109.1
	AF016266.1			AAB81180.1
	AF016268.1			AAC01565.1
	AF016849.1			AAC51778.1
	AF018657.1			AAB70577.1
	AF018658.1			AAB70578.1
	AF020501.1			AAB71412.1
	AF022386.1			AAB71949.1
	AF153687.1			AAF75587.1
	AF192548.1			AAF07175.1
	AK291216.1
	AK298602.1
	AL529460.3
	AY358277.1			AAQ88644.1
	BC001281.1			AAH01281.1
	BX538104.1			CAD98017.1
	CR541898.1			CAG46696.1
	DA738472.1
	DA889488.1
	FJ200482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1027718	Chr.8:22805950 - 23258334 on Build GRCh38	Gain	TNFRSF10A CHMP7 TNFRSF10C LOC389641 LOC101929237 TNFRSF10B PEBP4 LOC286059 LOC107984124 TNFRSF10D RHOBTB2 LOC254896
nsv1025672	Chr.8:22868571 - 23130480 on Build GRCh38	Gain	TNFRSF10C LOC101929237 TNFRSF10B PEBP4 LOC286059 LOC107984124 RHOBTB2 LOC254896
nsv1015967	Chr.8:23056273 - 23105040 on Build GRCh38	Loss	TNFRSF10C TNFRSF10B LOC286059 LOC254896
esv2759604	Chr.8:20675533 - 23254096 on Build GRCh38	Loss	FGF17 LOC101929172 SLC39A14 FAM160B2 LOC389641 LOC107986876 PPP3CC POLR3D XPO7 DMTN TNFRSF10D EGR3 CCAR2 CHMP7 TNFRSF10C BIN3-IT1 C8orf58 LGI3 TNFRSF10B PEBP4 LOC100507071 HR LOC254896 TNFRSF10A LOC286114 REEP4 GFRA2 SFTPC PHYHIP BMP1 LOC107984124 NUDT18 NPM2 LOC102467222 DOK2 LOC101929237 PIWIL2 LOC286059 MIR320A SORBS3 PDLIM2 RHOBTB2 BIN3
nsv1017570	Chr.8:22969562 - 23544783 on Build GRCh38	Gain	TNFRSF10A LOC389641 LOC100507156 LOC107984124 TNFRSF10D ENTPD4 CHMP7 TNFRSF10C TNFRSF10B SLC25A37 R3HCC1 LOC286059 LOXL2 RHOBTB2 LOC254896
esv2736750	Chr.8:23028863 - 23201144 on Build GRCh38	Deletion	TNFRSF10A TNFRSF10C TNFRSF10B LOC286059 TNFRSF10D LOC254896

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding