Hs03660637_cn

• Gene Symbol: LOC286059
• Assay Reference Genome Location: Chr.8:23068294 on build GRCh38
• Cytoband: 8p21.3

Target Gene Details

• Entrez Gene ID: 286059
• Gene Name: tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain pseudogene
• Gene Aliases: -
• Location: Chr.8:23068229-23083619 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC286059	NR_038873.1
	AK024295.1

Target Gene Details

• Entrez Gene ID: 8795
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Location: Chr.8:23020133-23069187 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TNFRSF10B	NM_003842.4			NP_003833.4
	NM_147187.2			NP_671716.2
	NR_027140.1
	AB451272.1
	AB451399.1
	AF012535.1			AAB67103.1
	AF012628.1			AAB67109.1
	AF016266.1			AAB81180.1
	AF016268.1			AAC01565.1
	AF016849.1			AAC51778.1
	AF018657.1			AAB70577.1
	AF018658.1			AAB70578.1
	AF020501.1			AAB71412.1
	AF022386.1			AAB71949.1
	AF153687.1			AAF75587.1
	AF192548.1			AAF07175.1
	AK291216.1
	AK298602.1
	AL529460.3
	AY358277.1			AAQ88644.1
	BC001281.1			AAH01281.1
	BX538104.1			CAD98017.1
	CR541898.1			CAG46696.1
	DA738472.1
	DA889488.1
	FJ200482.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1027718	Chr.8:22805950 - 23258334 on Build GRCh38	Gain	LOC254896 LOC286059 TNFRSF10C TNFRSF10D LOC389641 TNFRSF10B PEBP4 CHMP7 RHOBTB2 LOC101929237 TNFRSF10A LOC107984124
nsv1025672	Chr.8:22868571 - 23130480 on Build GRCh38	Gain	LOC254896 LOC286059 TNFRSF10C TNFRSF10B PEBP4 RHOBTB2 LOC101929237 LOC107984124
nsv1015967	Chr.8:23056273 - 23105040 on Build GRCh38	Loss	LOC254896 LOC286059 TNFRSF10C TNFRSF10B
esv2759604	Chr.8:20675533 - 23254096 on Build GRCh38	Loss	LOC254896 REEP4 CCAR2 SFTPC PHYHIP LGI3 PEBP4 RHOBTB2 MIR320A PIWIL2 LOC286114 BMP1 PDLIM2 LOC100507071 FAM160B2 NPM2 TNFRSF10D LOC389641 CHMP7 LOC101929237 DMTN LOC102467222 LOC107986876 LOC286059 SLC39A14 FGF17 BIN3-IT1 NUDT18 TNFRSF10C C8orf58 TNFRSF10B EGR3 HR PPP3CC SORBS3 BIN3 GFRA2 POLR3D LOC101929172 XPO7 DOK2 TNFRSF10A LOC107984124
esv2736750	Chr.8:23028863 - 23201144 on Build GRCh38	Deletion	LOC254896 LOC286059 TNFRSF10C TNFRSF10D TNFRSF10B TNFRSF10A
nsv1017570	Chr.8:22969562 - 23544783 on Build GRCh38	Gain	LOC254896 LOC286059 LOC100507156 R3HCC1 TNFRSF10C TNFRSF10B RHOBTB2 ENTPD4 TNFRSF10D LOC389641 CHMP7 LOXL2 SLC25A37 TNFRSF10A LOC107984124

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding