Hs03699766_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137311258 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 29

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1
	BU947354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF208 NELFB NRARP EXD3 NDOR1 TPRN FAM166A CYSRT1 RNF224 SSNA1 TOR4A TUBB4B TMEM203 C9orf173-AS1 STPG3 SLC34A3 ANAPC2
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	FAM166A CYSRT1 RNF224 NELFB TOR4A TUBB4B C9orf173-AS1 NRARP EXD3 STPG3 SLC34A3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	MAN1B1 RNF208 NELFB ABCA2 EXD3 NDOR1 LCN12 CCDC183 SAPCD2 C9orf142 PNPLA7 UAP1L1 STPG3 C9orf139 CLIC3 MIR7114 NRARP TPRN PTGDS PHPT1 NPDC1 RNF224 SSNA1 TOR4A TMEM210 TMEM203 LOC101930307 MAMDC4 C8G C9orf172 MAN1B1-AS1 EDF1 MIR4292 FAM166A CYSRT1 TUBB4B ANAPC2 LRRC26 MIR4479 MIR3621 RABL6 TRAF2 DPP7 ENTPD8 NSMF CCDC183-AS1 ENTPD2 C9orf173-AS1 FBXW5 FUT7 LCNL1 SLC34A3 GRIN1 NOXA1 PRR31
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 ENTPD8 NOXA1
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	MIR3621 RNF208 NELFB NRARP EXD3 NDOR1 TPRN FAM166A CYSRT1 RNF224 SSNA1 TOR4A TMEM210 TUBB4B TMEM203 C9orf173-AS1 STPG3 SLC34A3 ANAPC2 GRIN1 LRRC26
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	MIR3621 RNF208 NELFB NRARP EXD3 NDOR1 ENTPD8 TPRN FAM166A CYSRT1 RNF224 SSNA1 TOR4A TMEM210 TUBB4B TMEM203 C9orf173-AS1 STPG3 SLC34A3 ANAPC2 GRIN1 LRRC26 NOXA1
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	MAN1B1 RNF208 NELFB ABCA2 EXD3 NDOR1 EGFL7 LCN12 CCDC183 SAPCD2 FAM69B C9orf142 UAP1L1 LINC01451 STPG3 C9orf139 CLIC3 NRARP MIR6722 TPRN LOC100128593 PTGDS PHPT1 NPDC1 RNF224 SSNA1 TOR4A TMEM210 TMEM203 LOC101930307 MAMDC4 LCN10 SNHG7 C8G C9orf172 MAN1B1-AS1 SNORA17A EDF1 MIR4292 FAM166A CYSRT1 TUBB4B ANAPC2 LRRC26 MIR4479 MIR3621 TMEM141 RABL6 LCN15 SNORA17B TRAF2 DPP7 HSPC324 LCN6 AGPAT2 CCDC183-AS1 ENTPD2 C9orf173-AS1 FBXW5 FUT7 LCNL1 SLC34A3 GRIN1 LCN8 MIR126 PRR31
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	TOR4A NRARP EXD3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding