Hs03711093_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137426595 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	AB095031.1			BAC76710.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	ENTPD8 EXD3 NOXA1
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	ENTPD8 EXD3 NOXA1 MIR7114 NSMF PNPLA7
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NPDC1 FAM166A C9orf173-AS1 C9orf142 TPRN RNF224 MIR4479 NSMF DPP7 MAN1B1-AS1 FUT7 ANAPC2 CCDC183-AS1 MIR3621 C8G CYSRT1 MAN1B1 TMEM203 NDOR1 LCNL1 NRARP TMEM210 LRRC26 NELFB C9orf139 SLC34A3 UAP1L1 TOR4A TRAF2 NOXA1 MIR7114 RABL6 PNPLA7 MAMDC4 CLIC3 SSNA1 RNF208 ABCA2 PRR31 EDF1 C9orf172 LCN12 SAPCD2 ENTPD2 TUBB4B PHPT1 LOC101930307 ENTPD8 CCDC183 GRIN1 PTGDS EXD3 STPG3 FBXW5 MIR4292
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	ENTPD8 EXD3 NOXA1
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	ENTPD8 EXD3 NOXA1
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	SLC34A3 FAM166A TOR4A C9orf173-AS1 NOXA1 TMEM203 NDOR1 TPRN RNF224 NRARP TMEM210 SSNA1 TUBB4B RNF208 ENTPD8 GRIN1 ANAPC2 EXD3 LRRC26 MIR3621 NELFB STPG3 CYSRT1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding