Hs03712685_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137178721 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	MAN1B1-AS1 NDOR1 RNF224 UAP1L1 SSNA1 SLC34A3 GRIN1 MAN1B1 LRRC26 TMEM203 TMEM210 CYSRT1 DPP7 ANAPC2 LOC101930307 RNF208 TPRN MIR3621
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	FAM166A NDOR1 NRARP NELFB EXD3 STPG3 RNF224 SSNA1 SLC34A3 TMEM203 CYSRT1 TOR4A C9orf173-AS1 ANAPC2 RNF208 TPRN TUBB4B
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C8G MIR7114 MAN1B1 TMEM203 MIR4479 NOXA1 CCDC183 DPP7 TOR4A ANAPC2 NPDC1 C9orf172 TUBB4B NSMF TRAF2 SAPCD2 NRARP RNF224 RABL6 SSNA1 ABCA2 TMEM210 LOC101930307 RNF208 ENTPD2 CLIC3 MIR3621 FAM166A C9orf142 EXD3 STPG3 PTGDS UAP1L1 SLC34A3 GRIN1 MAMDC4 LRRC26 MIR4292 PHPT1 FUT7 LCNL1 FBXW5 MAN1B1-AS1 PRR31 CCDC183-AS1 NDOR1 NELFB LCN12 ENTPD8 PNPLA7 C9orf139 CYSRT1 C9orf173-AS1 EDF1 TPRN
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	FAM166A NDOR1 NRARP NELFB EXD3 STPG3 RNF224 SSNA1 SLC34A3 GRIN1 LRRC26 TMEM203 TMEM210 CYSRT1 TOR4A C9orf173-AS1 ANAPC2 RNF208 TPRN TUBB4B MIR3621
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	MAN1B1-AS1 SAPCD2 UAP1L1 SSNA1 GRIN1 MAN1B1 LRRC26 C9orf139 FUT7 TMEM210 DPP7 ANAPC2 NPDC1 LOC101930307 ENTPD2 MIR3621
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	FAM166A NDOR1 NRARP NELFB EXD3 STPG3 RNF224 ENTPD8 SSNA1 SLC34A3 GRIN1 LRRC26 TMEM203 NOXA1 TMEM210 CYSRT1 TOR4A C9orf173-AS1 ANAPC2 RNF208 TPRN TUBB4B MIR3621
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C8G SNORA17B MIR6722 MAN1B1 TMEM203 MIR4479 CCDC183 DPP7 TOR4A ANAPC2 NPDC1 LINC01451 EGFL7 C9orf172 TUBB4B TRAF2 SAPCD2 NRARP RNF224 RABL6 SSNA1 LCN8 FAM69B LCN6 ABCA2 TMEM210 LOC101930307 RNF208 ENTPD2 AGPAT2 CLIC3 MIR3621 FAM166A SNORA17A C9orf142 EXD3 STPG3 PTGDS LCN15 UAP1L1 SLC34A3 GRIN1 MAMDC4 HSPC324 LRRC26 MIR4292 PHPT1 FUT7 LCN10 LCNL1 FBXW5 SNHG7 MAN1B1-AS1 PRR31 CCDC183-AS1 TMEM141 NDOR1 NELFB LCN12 LOC100128593 C9orf139 CYSRT1 C9orf173-AS1 EDF1 TPRN MIR126

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity