Hs03712685_cn

• Gene Symbol: ANAPC2
• Assay Reference Genome Location: Chr.9:137178721 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 29882
• Gene Name: anaphase promoting complex subunit 2
• Gene Aliases: APC2
• Location: Chr.9:137174784-137188605 on Build GRCh38
• Assay Gene Location: Within Intron 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ANAPC2	NM_013366.3			NP_037498.1
	AB037827.1			BAA92644.1
	AF191337.1			AAF05751.1
	AK294601.1
	BC001579.1			AAH01579.1
	BC009487.2			AAH09487.2
	BC032503.1			AAH32503.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv616007	Chr.9:137079368 - 137240666 on Build GRCh38	Loss	UAP1L1 ANAPC2 DPP7 GRIN1 TPRN TMEM210 RNF224 LRRC26 MIR3621 RNF208 CYSRT1 NDOR1 LOC101930307 SLC34A3 SSNA1 MAN1B1-AS1 TMEM203 MAN1B1
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	C9orf173-AS1 ANAPC2 TPRN FAM166A RNF224 EXD3 RNF208 CYSRT1 TOR4A NDOR1 SLC34A3 NRARP NELFB TUBB4B SSNA1 STPG3 TMEM203
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	GRIN1 PNPLA7 TMEM210 FAM166A NOXA1 LRRC26 C9orf172 EXD3 C9orf142 LCN12 EDF1 C8G NPDC1 PHPT1 FUT7 TMEM203 DPP7 MIR4292 TRAF2 RNF208 CYSRT1 RABL6 LOC101930307 NRARP LCNL1 TUBB4B MAN1B1-AS1 STPG3 CCDC183-AS1 CLIC3 SAPCD2 ENTPD2 UAP1L1 ANAPC2 PRR31 MAMDC4 ENTPD8 TPRN NSMF RNF224 TOR4A SLC34A3 C9orf139 NELFB SSNA1 MAN1B1 C9orf173-AS1 FBXW5 CCDC183 MIR3621 MIR7114 NDOR1 MIR4479 ABCA2 PTGDS
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	C9orf173-AS1 ANAPC2 GRIN1 TPRN TMEM210 FAM166A RNF224 LRRC26 EXD3 MIR3621 RNF208 CYSRT1 TOR4A NDOR1 SLC34A3 NRARP NELFB TUBB4B SSNA1 STPG3 TMEM203
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	C9orf173-AS1 ANAPC2 GRIN1 ENTPD8 TPRN TMEM210 FAM166A NOXA1 RNF224 LRRC26 EXD3 MIR3621 RNF208 CYSRT1 TOR4A NDOR1 SLC34A3 NRARP NELFB TUBB4B SSNA1 STPG3 TMEM203
esv2761561	Chr.9:137030185 - 137191593 on Build GRCh38	Gain	UAP1L1 ANAPC2 DPP7 GRIN1 TMEM210 LRRC26 MIR3621 LOC101930307 C9orf139 NPDC1 SSNA1 FUT7 MAN1B1-AS1 SAPCD2 MAN1B1 ENTPD2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	GRIN1 TMEM210 FAM166A LRRC26 C9orf172 EXD3 C9orf142 LCN12 EDF1 C8G NPDC1 SNHG7 PHPT1 FUT7 TMEM203 LCN8 LCN10 DPP7 MIR4292 SNORA17A TRAF2 AGPAT2 RNF208 CYSRT1 RABL6 LOC101930307 NRARP LCNL1 TUBB4B MAN1B1-AS1 STPG3 CCDC183-AS1 EGFL7 CLIC3 LOC100128593 SAPCD2 ENTPD2 UAP1L1 ANAPC2 PRR31 MAMDC4 TPRN LCN15 RNF224 MIR6722 TOR4A SLC34A3 C9orf139 SNORA17B NELFB SSNA1 MAN1B1 C9orf173-AS1 HSPC324 FBXW5 CCDC183 MIR3621 FAM69B NDOR1 MIR4479 MIR126 LINC01451 ABCA2 TMEM141 PTGDS LCN6

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic nuclear division
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K11-linked ubiquitination
positive regulation of synapse maturation

Function(s)

ubiquitin protein ligase binding
ubiquitin protein ligase activity