Hs03713063_cn

• Gene Symbol: NOXA1
• Assay Reference Genome Location: Chr.9:137428581 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10811
• Gene Name: NADPH oxidase activator 1
• Gene Aliases: NY-CO-31, SDCCAG31, p51NOX
• Location: Chr.9:137423372-137434406 on Build GRCh38
• Assay Gene Location: Overlaps Exon 4 - Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NOXA1	NM_001256067.1			NP_001242996.1
	NM_001256068.1			NP_001242997.1
	NM_006647.1			NP_006638.1
	XM_011518158.2			XP_011516460.1
	XM_011518159.1			XP_011516461.1
	XM_011518160.1			XP_011516462.1
	XM_017014220.1			XP_016869709.1
	AB095031.1			BAC76710.1
	AK098341.1
	AY255769.1			AAP13480.1
	AY927790.1			AAY16126.1
	AY927791.1			AAY16127.1
	BC041594.1			AAH41594.1
	BC110840.1			AAI10841.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1049808	Chr.9:137356366 - 137438026 on Build GRCh38	Gain	ENTPD8 NOXA1 EXD3
nsv951208	Chr.9:137379349 - 137467948 on Build GRCh38	Deletion	NSMF ENTPD8 NOXA1 EXD3 PNPLA7 MIR7114
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	EDF1 ENTPD8 C9orf139 TMEM210 C9orf142 ENTPD2 NDOR1 MAN1B1 FAM166A FBXW5 MIR4479 C9orf173-AS1 MAN1B1-AS1 LRRC26 NOXA1 PRR31 PNPLA7 CYSRT1 LOC101930307 NPDC1 FUT7 TRAF2 CLIC3 C9orf172 CCDC183-AS1 RABL6 ABCA2 SAPCD2 ANAPC2 NRARP RNF224 NELFB MIR3621 LCN12 STPG3 SSNA1 SLC34A3 RNF208 MIR7114 PHPT1 NSMF TMEM203 EXD3 MAMDC4 PTGDS GRIN1 CCDC183 TUBB4B LCNL1 DPP7 TOR4A TPRN UAP1L1 MIR4292 C8G
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	ENTPD8 NOXA1 EXD3
nsv6771	Chr.9:137412670 - 137444666 on Build GRCh38	Insertion	ENTPD8 NOXA1 EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TUBB4B ENTPD8 TMEM210 SSNA1 LRRC26 NOXA1 TOR4A TPRN CYSRT1 SLC34A3 RNF208 NDOR1 TMEM203 ANAPC2 EXD3 FAM166A NRARP RNF224 GRIN1 NELFB MIR3621 C9orf173-AS1 STPG3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protein-binding activity modulator

Gene Ontology Categories:

Process(es)

superoxide metabolic process
regulation of hydrogen peroxide metabolic process
positive regulation of catalytic activity
regulation of respiratory burst

Function(s)

protein binding
superoxide-generating NADPH oxidase activator activity
SH3 domain binding
enzyme binding
Rac GTPase binding