Hs03713884_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136979702 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AA621632.1
	AK075333.1
	AK312817.1
	AY026356.1			AAK07679.1
	BC005939.1			AAH05939.1
	BG037037.1
	BM686612.1
	BT019921.1			AAV38724.1
	BT019922.1			AAV38725.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13008n54	Chr.9:136977199 - 136980285 on Build GRCh38	Loss	PTGDS
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	GRIN1 C9orf142 LCNL1 TMEM210 FUT7 NPDC1 MIR3621 ENTPD2 PTGDS LRRC26 ABCA2 SAPCD2 UAP1L1 MAN1B1 LOC101930307 DPP7 C9orf139 CLIC3 PRR31 MAN1B1-AS1
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	C9orf142 LCNL1 CLIC3 PRR31 PTGDS ABCA2
nsv615992	Chr.9:136975638 - 136980181 on Build GRCh38	Loss	PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	C9orf142 C8G TMEM141 PTGDS ABCA2 TRAF2 LCN8 CCDC183 CLIC3 CCDC183-AS1 PRR31 FBXW5 EDF1 LCNL1 LOC100128593 MAMDC4 LCN15 LCN12 MIR6722 LCN10 RABL6 PHPT1 LCN6 MIR4479 MIR4292 C9orf172
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C8G SSNA1 TPRN LRRC26 TRAF2 CCDC183 C9orf139 CLIC3 PRR31 GRIN1 NSMF RNF208 TMEM210 ANAPC2 NPDC1 ENTPD2 C9orf173-AS1 NDOR1 TOR4A LOC101930307 STPG3 TUBB4B MIR4479 C9orf172 NRARP C9orf142 FUT7 MIR3621 PTGDS ABCA2 ENTPD8 SAPCD2 CYSRT1 UAP1L1 MAN1B1 EXD3 CCDC183-AS1 RNF224 FBXW5 EDF1 LCNL1 PNPLA7 TMEM203 MAMDC4 FAM166A SLC34A3 NELFB LCN12 NOXA1 DPP7 MIR7114 RABL6 PHPT1 MIR4292 MAN1B1-AS1
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	C9orf142 LCNL1 C8G FUT7 NPDC1 ENTPD2 PTGDS ABCA2 SAPCD2 UAP1L1 MAN1B1 LCN12 LOC101930307 DPP7 C9orf139 CLIC3 PRR31 MAN1B1-AS1
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	HSPC324 C8G TMEM141 LRRC26 TRAF2 CCDC183 C9orf139 CLIC3 PRR31 SNHG7 AGPAT2 GRIN1 TMEM210 INPP5E NPDC1 ENTPD2 LCN15 SEC16A NOTCH1 MIR4673 LOC101930307 MIR6722 LCN6 MIR4479 C9orf172 C9orf163 DNLZ C9orf142 LINC01451 FUT7 MIR3621 PTGDS PMPCA MIR4674 ABCA2 LCN8 SNAPC4 SAPCD2 SDCCAG3 MIR126 UAP1L1 MAN1B1 FAM69B EGFL7 SNORA17B CCDC183-AS1 SNORA17A FBXW5 EDF1 CARD9 LCNL1 LOC100128593 MAMDC4 LCN12 DPP7 LCN10 RABL6 PHPT1 NALT1 MIR4292 MAN1B1-AS1
nsv616002	Chr.9:136977855 - 136981118 on Build GRCh38	Loss	PTGDS
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	HSPC324 C8G TMEM141 SSNA1 TPRN LRRC26 TRAF2 CCDC183 C9orf139 CLIC3 PRR31 SNHG7 AGPAT2 GRIN1 RNF208 TMEM210 ANAPC2 NPDC1 ENTPD2 LCN15 C9orf173-AS1 NDOR1 TOR4A LOC101930307 MIR6722 STPG3 TUBB4B LCN6 MIR4479 C9orf172 NRARP C9orf142 LINC01451 FUT7 MIR3621 PTGDS ABCA2 LCN8 SAPCD2 CYSRT1 MIR126 UAP1L1 MAN1B1 FAM69B EGFL7 EXD3 SNORA17B CCDC183-AS1 RNF224 SNORA17A FBXW5 EDF1 LCNL1 LOC100128593 TMEM203 MAMDC4 FAM166A SLC34A3 NELFB LCN12 DPP7 LCN10 RABL6 PHPT1 MIR4292 MAN1B1-AS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding