Hs03713884_cn

• Gene Symbol: PTGDS
• Assay Reference Genome Location: Chr.9:136979702 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 5730
• Gene Name: prostaglandin D2 synthase
• Gene Aliases: L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
• Location: Chr.9:136977504-136981742 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTGDS	NM_000954.5			NP_000945.3
	AA621632.1
	AK075333.1
	AK312817.1
	AY026356.1			AAK07679.1
	BC005939.1			AAH05939.1
	BG037037.1
	BM686612.1
	BT019921.1			AAV38724.1
	BT019922.1			AAV38725.1
	M61900.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv615997	Chr.9:136977199 - 136984376 on Build GRCh38	Loss	LCNL1 PTGDS
nsv615991	Chr.9:136972675 - 137011907 on Build GRCh38	Loss	PRR31 LCNL1 ABCA2 C9orf142 PTGDS CLIC3
dgv13007n54	Chr.9:136966179 - 137173890 on Build GRCh38	Loss	NPDC1 SAPCD2 C9orf142 LOC101930307 TMEM210 GRIN1 MIR3621 PRR31 ENTPD2 LCNL1 ABCA2 MAN1B1 LRRC26 DPP7 C9orf139 PTGDS MAN1B1-AS1 UAP1L1 CLIC3 FUT7
nsv615993	Chr.9:136975638 - 136983246 on Build GRCh38	Gain	LCNL1 PTGDS
nsv818738	Chr.9:136740043 - 137009585 on Build GRCh38	Gain	MIR6722 LOC100128593 MIR4479 LCN8 LCN6 LCNL1 TRAF2 MIR4292 LCN12 PHPT1 PTGDS MAMDC4 TMEM141 FBXW5 CLIC3 EDF1 C9orf142 LCN15 PRR31 ABCA2 CCDC183-AS1 C8G CCDC183 RABL6 LCN10 C9orf172
nsv615994	Chr.9:136975930 - 136979942 on Build GRCh38	Gain	PTGDS
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	NPDC1 TUBB4B SLC34A3 NELFB TOR4A TMEM210 GRIN1 MIR4479 LCNL1 TRAF2 TMEM203 NSMF MIR4292 PHPT1 MAMDC4 CLIC3 ENTPD8 PNPLA7 RNF208 C9orf142 LOC101930307 TPRN MIR3621 STPG3 ABCA2 CCDC183-AS1 C9orf139 C8G RABL6 UAP1L1 C9orf172 NOXA1 SSNA1 ANAPC2 C9orf173-AS1 MAN1B1 NRARP LCN12 PTGDS MAN1B1-AS1 FBXW5 FAM166A EDF1 SAPCD2 MIR7114 NDOR1 PRR31 ENTPD2 EXD3 LRRC26 DPP7 CCDC183 RNF224 CYSRT1 FUT7
nsv951206	Chr.9:136944849 - 137114548 on Build GRCh38	Deletion	NPDC1 SAPCD2 C9orf142 LOC101930307 PRR31 ENTPD2 LCNL1 ABCA2 MAN1B1 DPP7 C9orf139 C8G LCN12 PTGDS MAN1B1-AS1 UAP1L1 CLIC3 FUT7
nsv616002	Chr.9:136977855 - 136981118 on Build GRCh38	Loss	PTGDS
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	NPDC1 TMEM210 LOC100128593 GRIN1 MIR4479 LCN8 LCN6 LCNL1 LINC01451 TRAF2 MIR4292 PHPT1 MAMDC4 TMEM141 CLIC3 INPP5E C9orf142 LOC101930307 HSPC324 C9orf163 MIR3621 LCN15 SNAPC4 SNHG7 ABCA2 CCDC183-AS1 C9orf139 C8G DNLZ RABL6 UAP1L1 LCN10 SEC16A C9orf172 PMPCA MIR6722 FAM69B MIR4673 MIR126 CARD9 MAN1B1 SNORA17B LCN12 PTGDS MAN1B1-AS1 SNORA17A FBXW5 EGFL7 EDF1 SAPCD2 NALT1 SDCCAG3 PRR31 ENTPD2 NOTCH1 MIR4674 LRRC26 DPP7 CCDC183 AGPAT2 FUT7
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	NPDC1 TUBB4B SLC34A3 NELFB TOR4A TMEM210 LOC100128593 GRIN1 MIR4479 LCN8 LCN6 LCNL1 LINC01451 TRAF2 TMEM203 MIR4292 PHPT1 MAMDC4 TMEM141 CLIC3 RNF208 C9orf142 LOC101930307 HSPC324 TPRN MIR3621 STPG3 LCN15 SNHG7 ABCA2 CCDC183-AS1 C9orf139 C8G RABL6 UAP1L1 LCN10 C9orf172 SSNA1 MIR6722 FAM69B ANAPC2 C9orf173-AS1 MIR126 MAN1B1 SNORA17B NRARP LCN12 PTGDS MAN1B1-AS1 SNORA17A FBXW5 EGFL7 FAM166A EDF1 SAPCD2 NDOR1 PRR31 ENTPD2 EXD3 LRRC26 DPP7 CCDC183 RNF224 CYSRT1 AGPAT2 FUT7

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transfer/carrier protein

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
transport
cyclooxygenase pathway
regulation of circadian sleep/wake cycle, sleep
response to glucocorticoid
negative regulation of male germ cell proliferation

Function(s)

prostaglandin-D synthase activity
transporter activity
retinoid binding
fatty acid binding
protein binding
small molecule binding