Hs03714785_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137324551 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	RNF224 TPRN RNF208 TMEM203 TUBB4B C9orf173-AS1 FAM166A SLC34A3 NRARP CYSRT1 NELFB ANAPC2 EXD3 SSNA1 STPG3 NDOR1 TOR4A
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	RNF224 NRARP CYSRT1 NELFB TUBB4B C9orf173-AS1 EXD3 FAM166A STPG3 TOR4A SLC34A3
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 ENTPD8 NOXA1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	ABCA2 LCNL1 TUBB4B CCDC183-AS1 FAM166A SAPCD2 MIR4479 SLC34A3 C8G ANAPC2 LCN12 STPG3 ENTPD8 NDOR1 PTGDS TPRN FBXW5 TMEM203 C9orf139 UAP1L1 GRIN1 FUT7 NPDC1 LOC101930307 EXD3 NSMF MAN1B1 CLIC3 RNF208 MAMDC4 DPP7 PRR31 MIR4292 MIR3621 MIR7114 CCDC183 CYSRT1 PNPLA7 TRAF2 PHPT1 MAN1B1-AS1 NOXA1 TOR4A C9orf142 RNF224 C9orf173-AS1 EDF1 TMEM210 LRRC26 NRARP NELFB RABL6 ENTPD2 SSNA1 C9orf172
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	RNF224 TPRN RNF208 TMEM203 TUBB4B C9orf173-AS1 FAM166A TMEM210 LRRC26 MIR3621 SLC34A3 GRIN1 NRARP CYSRT1 NELFB ANAPC2 EXD3 SSNA1 STPG3 NDOR1 TOR4A
nsv6770	Chr.9:137316337 - 137347440 on Build GRCh38	Insertion	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	RNF224 TPRN RNF208 TMEM203 TUBB4B C9orf173-AS1 FAM166A TMEM210 LRRC26 MIR3621 SLC34A3 GRIN1 NRARP CYSRT1 NELFB ANAPC2 EXD3 SSNA1 STPG3 ENTPD8 NOXA1 NDOR1 TOR4A
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	NRARP EXD3 TOR4A
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	ABCA2 LCNL1 TUBB4B LOC100128593 CCDC183-AS1 FAM166A SAPCD2 MIR4479 SLC34A3 SNORA17A C8G ANAPC2 LCN12 STPG3 LCN10 NDOR1 PTGDS LCN8 TPRN FBXW5 LCN15 TMEM203 C9orf139 AGPAT2 FAM69B SNHG7 UAP1L1 EGFL7 GRIN1 LCN6 FUT7 NPDC1 LOC101930307 EXD3 MAN1B1 MIR126 CLIC3 RNF208 MAMDC4 DPP7 PRR31 MIR4292 MIR3621 LINC01451 CCDC183 HSPC324 CYSRT1 TRAF2 PHPT1 MAN1B1-AS1 TOR4A C9orf142 RNF224 SNORA17B C9orf173-AS1 EDF1 TMEM141 TMEM210 LRRC26 NRARP MIR6722 NELFB RABL6 ENTPD2 SSNA1 C9orf172

More Information

Additional Information:

For this assay, SNP(s) [rs144589250] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding