Hs03714785_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137324551 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TOR4A TMEM203 RNF208 NDOR1 NELFB C9orf173-AS1 NRARP CYSRT1 TUBB4B RNF224 FAM166A TPRN EXD3 SLC34A3 ANAPC2 SSNA1 STPG3
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	TOR4A FAM166A NELFB EXD3 C9orf173-AS1 SLC34A3 NRARP STPG3 CYSRT1 TUBB4B RNF224
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	RNF208 PHPT1 NSMF CYSRT1 EDF1 TRAF2 DPP7 SLC34A3 MIR7114 ENTPD8 FBXW5 FUT7 TMEM203 UAP1L1 NELFB NRARP GRIN1 TUBB4B LRRC26 PTGDS CLIC3 NPDC1 EXD3 MAN1B1 C9orf142 ENTPD2 NDOR1 C9orf172 CCDC183-AS1 LCN12 RNF224 LOC101930307 MIR4479 MIR4292 TPRN ANAPC2 SSNA1 STPG3 TMEM210 TOR4A NOXA1 C9orf173-AS1 PNPLA7 LCNL1 MAN1B1-AS1 MIR3621 ABCA2 PRR31 FAM166A C9orf139 MAMDC4 RABL6 C8G SAPCD2 CCDC183
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	NOXA1 EXD3 ENTPD8
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TOR4A TMEM203 RNF208 NDOR1 NELFB C9orf173-AS1 NRARP MIR3621 CYSRT1 GRIN1 TUBB4B RNF224 LRRC26 FAM166A TPRN EXD3 SLC34A3 ANAPC2 SSNA1 STPG3 TMEM210
nsv49	Chr.9:137316337 - 137334193 on Build GRCh38	Insertion	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TOR4A TMEM203 RNF208 NOXA1 NDOR1 NELFB C9orf173-AS1 NRARP MIR3621 CYSRT1 GRIN1 TUBB4B RNF224 LRRC26 FAM166A TPRN EXD3 SLC34A3 ANAPC2 SSNA1 STPG3 ENTPD8 TMEM210
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	RNF208 PHPT1 FAM69B MIR6722 CYSRT1 EDF1 TRAF2 DPP7 SLC34A3 AGPAT2 LCN10 FBXW5 FUT7 TMEM203 TMEM141 UAP1L1 NELFB LCN15 SNHG7 NRARP SNORA17B GRIN1 TUBB4B LRRC26 PTGDS CLIC3 NPDC1 EXD3 MAN1B1 C9orf142 HSPC324 LINC01451 ENTPD2 NDOR1 C9orf172 CCDC183-AS1 LCN12 RNF224 LOC101930307 MIR4479 LCN6 MIR4292 TPRN ANAPC2 SSNA1 STPG3 MIR126 TMEM210 TOR4A LOC100128593 C9orf173-AS1 LCNL1 MAN1B1-AS1 MIR3621 ABCA2 LCN8 PRR31 EGFL7 FAM166A C9orf139 MAMDC4 RABL6 SNORA17A C8G SAPCD2 CCDC183
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	TOR4A EXD3 NRARP

More Information

Additional Information:

For this assay, SNP(s) [rs144589250] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding