Hs03716347_cn

• Gene Symbol: AGPAT2
• Assay Reference Genome Location: Chr.9:136675710 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10555
• Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
• Gene Aliases: 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
• Location: Chr.9:136673143-136687459 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGPAT2	NM_001012727.1			NP_001012745.1
	NM_006412.3			NP_006403.2
	AF000237.1			AAC51649.1
	AF011374.1			AAB64299.1
	BC000026.2			AAH00026.1
	BC004529.2			AAH04529.1
	BC007269.1			AAH07269.1
	BC019292.1			AAH19292.1
	BF347518.1
	U56418.2			AAB58776.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13005n54	Chr.9:136605258 - 136696482 on Build GRCh38	Loss	HSPC324 EGFL7 LINC01451 MIR126 AGPAT2
nsv509334	Chr.9:136514168 - 136724663 on Build GRCh38	Insertion	HSPC324 FAM69B SNHG7 NALT1 EGFL7 NOTCH1 LINC01451 MIR4674 MIR126 MIR4673 AGPAT2
nsv951203	Chr.9:136562849 - 136770848 on Build GRCh38	Deletion	FAM69B SNHG7 LCN8 LCN10 EGFL7 LINC01451 HSPC324 SNORA17B MIR126 LOC100128593 LCN15 SNORA17A AGPAT2 MIR6722 LCN6
esv2739381	Chr.9:136675175 - 136675752 on Build GRCh38	Deletion	AGPAT2
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	C9orf163 FAM69B EGFL7 PHPT1 DPP7 ABCA2 LCNL1 GRIN1 MIR3621 ENTPD2 MAMDC4 MIR4292 RABL6 EDF1 PMPCA LCN15 LOC101930307 SNAPC4 NALT1 CCDC183-AS1 SAPCD2 CLIC3 INPP5E LCN12 C8G HSPC324 PTGDS UAP1L1 NPDC1 MAN1B1 SNORA17B LOC100128593 SNORA17A LCN8 LINC01451 C9orf139 CARD9 SDCCAG3 MAN1B1-AS1 SEC16A PRR31 TRAF2 C9orf172 TMEM210 FUT7 NOTCH1 MIR126 LRRC26 TMEM141 MIR6722 LCN6 SNHG7 LCN10 CCDC183 MIR4674 MIR4479 FBXW5 C9orf142 DNLZ MIR4673 AGPAT2
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	C9orf163 FAM69B LCN8 EGFL7 PHPT1 LINC01451 CARD9 SDCCAG3 MAMDC4 MIR4292 SEC16A TRAF2 C9orf172 RABL6 EDF1 NOTCH1 MIR126 PMPCA LCN15 TMEM141 MIR6722 LCN6 SNHG7 SNAPC4 NALT1 LCN10 CCDC183 MIR4674 CCDC183-AS1 INPP5E MIR4479 HSPC324 DNLZ GPSM1 SNORA17B LOC100128593 MIR4673 SNORA17A AGPAT2
nsv8579	Chr.9:136505432 - 136760256 on Build GRCh38	Gain	FAM69B SNHG7 NALT1 LCN8 LCN10 EGFL7 LINC01451 MIR4674 HSPC324 NOTCH1 SNORA17B MIR126 LOC100128593 LCN15 MIR4673 SNORA17A AGPAT2 MIR6722 LCN6
dgv955n27	Chr.9:136583078 - 136676165 on Build GRCh38	Loss	HSPC324 EGFL7 LINC01451 MIR126 AGPAT2
nsv1053781	Chr.9:136590694 - 136722927 on Build GRCh38	Gain	HSPC324 FAM69B EGFL7 LINC01451 MIR126 AGPAT2
dgv957n27	Chr.9:136619086 - 136725859 on Build GRCh38	Loss	HSPC324 FAM69B SNHG7 EGFL7 MIR126 AGPAT2
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	FAM69B EGFL7 PHPT1 DPP7 ABCA2 LCNL1 EXD3 GRIN1 MIR3621 SSNA1 ENTPD2 MAMDC4 MIR4292 FAM166A RABL6 EDF1 LCN15 LOC101930307 STPG3 CCDC183-AS1 SAPCD2 CLIC3 LCN12 C8G HSPC324 PTGDS TUBB4B UAP1L1 TMEM203 NRARP NPDC1 RNF208 MAN1B1 SNORA17B C9orf173-AS1 LOC100128593 RNF224 SNORA17A SLC34A3 LCN8 TPRN LINC01451 C9orf139 MAN1B1-AS1 CYSRT1 PRR31 TRAF2 C9orf172 TMEM210 FUT7 MIR126 LRRC26 TOR4A TMEM141 MIR6722 LCN6 NELFB SNHG7 LCN10 CCDC183 ANAPC2 NDOR1 MIR4479 FBXW5 C9orf142 AGPAT2

More Information

Additional Information:

For this assay, SNP(s) [rs114779139] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

positive regulation of cytokine production
positive regulation of cytokine-mediated signaling pathway
phospholipid metabolic process
phosphatidic acid biosynthetic process
epidermis development
CDP-diacylglycerol biosynthetic process
triglyceride biosynthetic process
response to antidepressant

Function(s)

1-acylglycerol-3-phosphate O-acyltransferase activity