Hs03716347_cn

• Gene Symbol: AGPAT2
• Assay Reference Genome Location: Chr.9:136675710 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 10555
• Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
• Gene Aliases: 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
• Location: Chr.9:136673143-136687459 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AGPAT2	NM_001012727.1			NP_001012745.1
	NM_006412.3			NP_006403.2
	AF000237.1			AAC51649.1
	AF011374.1			AAB64299.1
	BC000026.2			AAH00026.1
	BC004529.2			AAH04529.1
	BC007269.1			AAH07269.1
	BC019292.1			AAH19292.1
	BF347518.1
	U56418.2			AAB58776.2

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13005n54	Chr.9:136605258 - 136696482 on Build GRCh38	Loss	EGFL7 MIR126 AGPAT2 LINC01451 HSPC324
nsv509334	Chr.9:136514168 - 136724663 on Build GRCh38	Insertion	EGFL7 SNHG7 MIR4673 MIR126 FAM69B AGPAT2 LINC01451 NOTCH1 MIR4674 NALT1 HSPC324
nsv951203	Chr.9:136562849 - 136770848 on Build GRCh38	Deletion	LCN10 LCN6 EGFL7 FAM69B AGPAT2 LINC01451 SNORA17A LCN15 MIR6722 SNORA17B HSPC324 LOC100128593 SNHG7 MIR126 LCN8
esv2739381	Chr.9:136675175 - 136675752 on Build GRCh38	Deletion	AGPAT2
esv2759720	Chr.9:136356377 - 136932033 on Build GRCh38	Loss	C9orf172 SNAPC4 FAM69B AGPAT2 NOTCH1 EDF1 TMEM141 NALT1 TRAF2 PHPT1 SNHG7 MIR4673 LCN8 CCDC183 MIR4292 LCN10 LCN6 EGFL7 SEC16A C9orf163 LINC01451 MIR4479 SNORA17A LCN15 GPSM1 RABL6 MIR6722 SNORA17B HSPC324 INPP5E LOC100128593 CARD9 DNLZ CCDC183-AS1 MIR126 SDCCAG3 MAMDC4 MIR4674 PMPCA
nsv469918	Chr.9:136359865 - 137173890 on Build GRCh38	Loss	PRR31 ABCA2 C9orf172 MIR3621 SNAPC4 FAM69B AGPAT2 NOTCH1 TMEM141 NALT1 MAN1B1-AS1 TRAF2 PHPT1 CCDC183 MIR4292 C9orf163 LINC01451 SNORA17A C8G RABL6 PTGDS MIR6722 LCN12 HSPC324 DPP7 DNLZ CCDC183-AS1 MIR126 MAMDC4 MIR4674 C9orf139 PMPCA CLIC3 LOC101930307 C9orf142 EDF1 SNHG7 MIR4673 FUT7 LRRC26 UAP1L1 SAPCD2 LCN8 LCN10 LCN6 EGFL7 MAN1B1 FBXW5 SEC16A MIR4479 LCN15 SNORA17B INPP5E LOC100128593 CARD9 ENTPD2 SDCCAG3 NPDC1 GRIN1 LCNL1 TMEM210
nsv8579	Chr.9:136505432 - 136760256 on Build GRCh38	Gain	LCN10 LCN6 EGFL7 FAM69B AGPAT2 LINC01451 SNORA17A NOTCH1 LCN15 MIR6722 SNORA17B NALT1 HSPC324 LOC100128593 SNHG7 MIR4673 MIR126 MIR4674 LCN8
dgv955n27	Chr.9:136583078 - 136676165 on Build GRCh38	Loss	EGFL7 MIR126 AGPAT2 LINC01451 HSPC324
nsv1053781	Chr.9:136590694 - 136722927 on Build GRCh38	Gain	EGFL7 MIR126 FAM69B AGPAT2 LINC01451 HSPC324
dgv13006n54	Chr.9:136619086 - 136725859 on Build GRCh38	Loss	EGFL7 SNHG7 MIR126 FAM69B AGPAT2 HSPC324
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	RNF208 PRR31 ABCA2 C9orf172 MIR3621 FAM69B AGPAT2 NDOR1 TOR4A TMEM141 TUBB4B MAN1B1-AS1 TRAF2 PHPT1 STPG3 CCDC183 MIR4292 SSNA1 C9orf173-AS1 LINC01451 SNORA17A EXD3 C8G RABL6 PTGDS MIR6722 LCN12 HSPC324 DPP7 TPRN CCDC183-AS1 MIR126 TMEM203 FAM166A MAMDC4 C9orf139 CLIC3 RNF224 LOC101930307 SLC34A3 C9orf142 EDF1 SNHG7 FUT7 LRRC26 UAP1L1 SAPCD2 LCN8 CYSRT1 LCN10 LCN6 EGFL7 MAN1B1 FBXW5 MIR4479 LCN15 ANAPC2 SNORA17B LOC100128593 ENTPD2 NPDC1 GRIN1 NRARP NELFB LCNL1 TMEM210

More Information

Additional Information:

For this assay, SNP(s) [rs114779139] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

acyltransferase

Gene Ontology Categories:

Process(es)

positive regulation of cytokine production
positive regulation of cytokine-mediated signaling pathway
phospholipid metabolic process
phosphatidic acid biosynthetic process
epidermis development
CDP-diacylglycerol biosynthetic process
triglyceride biosynthetic process
response to antidepressant

Function(s)

1-acylglycerol-3-phosphate O-acyltransferase activity