Hs03720524_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137317562 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 29

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1
	BU947354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	ANAPC2 TMEM203 NDOR1 NELFB C9orf173-AS1 CYSRT1 NRARP SSNA1 TOR4A STPG3 TUBB4B FAM166A SLC34A3 TPRN RNF208 RNF224 EXD3
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	TOR4A STPG3 TUBB4B FAM166A NELFB SLC34A3 RNF224 C9orf173-AS1 CYSRT1 NRARP EXD3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	C9orf139 TMEM210 C9orf142 MAN1B1 MIR3621 TRAF2 STPG3 PHPT1 MIR4292 PNPLA7 CCDC183 TMEM203 FBXW5 ENTPD8 MIR4479 CYSRT1 NPDC1 C8G LRRC26 MAN1B1-AS1 PRR31 TPRN UAP1L1 RNF224 MAMDC4 LCN12 SAPCD2 NSMF LCNL1 C9orf173-AS1 GRIN1 C9orf172 ABCA2 SSNA1 TOR4A ENTPD2 TUBB4B EXD3 RABL6 ANAPC2 LOC101930307 NDOR1 NELFB DPP7 CCDC183-AS1 NRARP CLIC3 NOXA1 EDF1 FAM166A MIR7114 SLC34A3 RNF208 FUT7 PTGDS
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	NOXA1 ENTPD8 EXD3
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	ANAPC2 TMEM203 TMEM210 NDOR1 NELFB C9orf173-AS1 CYSRT1 NRARP GRIN1 MIR3621 SSNA1 TOR4A LRRC26 STPG3 TUBB4B FAM166A SLC34A3 TPRN RNF208 RNF224 EXD3
nsv49	Chr.9:137316337 - 137334193 on Build GRCh38	Insertion	EXD3
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	ANAPC2 TMEM203 TMEM210 NDOR1 ENTPD8 NELFB C9orf173-AS1 CYSRT1 NRARP GRIN1 MIR3621 SSNA1 TOR4A NOXA1 LRRC26 STPG3 TUBB4B FAM166A SLC34A3 TPRN RNF208 RNF224 EXD3
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	C9orf139 TMEM210 C9orf142 MAN1B1 MIR3621 SNORA17A TMEM141 TRAF2 STPG3 PHPT1 MIR4292 CCDC183 TMEM203 FBXW5 AGPAT2 SNHG7 MIR4479 LCN8 HSPC324 CYSRT1 NPDC1 MIR6722 C8G LINC01451 LRRC26 MAN1B1-AS1 PRR31 TPRN SNORA17B UAP1L1 RNF224 MAMDC4 LOC100128593 FAM69B LCN12 SAPCD2 LCNL1 C9orf173-AS1 GRIN1 C9orf172 ABCA2 SSNA1 TOR4A ENTPD2 TUBB4B LCN15 EXD3 RABL6 LCN6 ANAPC2 LOC101930307 NDOR1 NELFB LCN10 DPP7 CCDC183-AS1 MIR126 NRARP CLIC3 EGFL7 EDF1 FAM166A SLC34A3 RNF208 FUT7 PTGDS
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	TOR4A NRARP EXD3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding