Hs03725101_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137307376 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 31

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1
	BU947354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	SSNA1 EXD3 SLC34A3 ANAPC2 STPG3 TPRN NRARP RNF224 C9orf173-AS1 TOR4A NDOR1 RNF208 CYSRT1 TMEM203 TUBB4B FAM166A NELFB
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	RNF224 EXD3 C9orf173-AS1 SLC34A3 TOR4A CYSRT1 STPG3 NRARP TUBB4B FAM166A NELFB
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	MIR3621 SSNA1 EXD3 MIR4479 C9orf172 C9orf139 RABL6 TPRN LRRC26 MIR4292 C9orf173-AS1 NDOR1 RNF208 C8G CYSRT1 ENTPD8 GRIN1 NELFB FBXW5 STPG3 PRR31 ENTPD2 CCDC183 RNF224 PTGDS TOR4A MAN1B1 TMEM203 ANAPC2 SAPCD2 LCN12 NRARP LCNL1 EDF1 PNPLA7 UAP1L1 MAN1B1-AS1 NOXA1 TUBB4B C9orf142 NSMF PHPT1 MAMDC4 ABCA2 SLC34A3 CCDC183-AS1 FUT7 DPP7 TMEM210 TRAF2 LOC101930307 MIR7114 CLIC3 NPDC1 FAM166A
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 NOXA1 ENTPD8
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	MIR3621 SSNA1 EXD3 SLC34A3 ANAPC2 STPG3 TPRN LRRC26 NRARP TMEM210 RNF224 C9orf173-AS1 TOR4A NDOR1 RNF208 CYSRT1 TMEM203 TUBB4B GRIN1 FAM166A NELFB
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	MIR3621 SSNA1 EXD3 SLC34A3 ANAPC2 STPG3 TPRN LRRC26 NRARP TMEM210 RNF224 NOXA1 C9orf173-AS1 TOR4A NDOR1 RNF208 CYSRT1 TMEM203 TUBB4B ENTPD8 GRIN1 FAM166A NELFB
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	MIR3621 HSPC324 SSNA1 EXD3 LCN8 MIR4479 C9orf172 C9orf139 RABL6 TPRN LRRC26 MIR4292 C9orf173-AS1 LCN6 NDOR1 RNF208 MIR6722 C8G CYSRT1 GRIN1 NELFB LCN15 FBXW5 SNHG7 STPG3 SNORA17B PRR31 ENTPD2 FAM69B CCDC183 RNF224 PTGDS TOR4A MAN1B1 LINC01451 TMEM203 LCN10 ANAPC2 SAPCD2 EGFL7 LCN12 NRARP LCNL1 EDF1 MIR126 UAP1L1 MAN1B1-AS1 TUBB4B LOC100128593 AGPAT2 C9orf142 PHPT1 MAMDC4 ABCA2 SLC34A3 CCDC183-AS1 FUT7 DPP7 TMEM210 TRAF2 LOC101930307 TMEM141 SNORA17A CLIC3 NPDC1 FAM166A
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	EXD3 TOR4A NRARP

More Information

Additional Information:

For this assay, SNP(s) [rs113267547] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding