Hs03725101_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137307376 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 31

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK094438.1			BAC04356.1
	BU947354.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv13009n54	Chr.9:137173890 - 137327859 on Build GRCh38	Loss	TPRN RNF224 NRARP EXD3 TUBB4B TOR4A STPG3 SSNA1 FAM166A SLC34A3 TMEM203 RNF208 ANAPC2 C9orf173-AS1 NELFB NDOR1 CYSRT1
dgv13011n54	Chr.9:137223996 - 137338927 on Build GRCh38	Loss	STPG3 FAM166A RNF224 SLC34A3 NRARP C9orf173-AS1 EXD3 NELFB TUBB4B CYSRT1 TOR4A
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	ENTPD8 EXD3 NOXA1
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TPRN PNPLA7 C9orf172 ENTPD2 FBXW5 TMEM210 NOXA1 TUBB4B DPP7 CLIC3 MAN1B1 GRIN1 CCDC183-AS1 ANAPC2 EDF1 NDOR1 MAMDC4 RNF224 C8G ABCA2 NPDC1 SAPCD2 C9orf142 MIR4479 LRRC26 PRR31 SLC34A3 RNF208 C9orf173-AS1 LCNL1 MIR3621 NELFB NSMF LOC101930307 ENTPD8 MIR7114 SSNA1 LCN12 TMEM203 C9orf139 PTGDS CYSRT1 FUT7 TRAF2 PHPT1 NRARP EXD3 TOR4A STPG3 UAP1L1 FAM166A CCDC183 MAN1B1-AS1 RABL6 MIR4292
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	TPRN RNF224 NRARP TMEM210 EXD3 TUBB4B TOR4A STPG3 SSNA1 GRIN1 FAM166A LRRC26 SLC34A3 TMEM203 RNF208 ANAPC2 C9orf173-AS1 MIR3621 NELFB NDOR1 CYSRT1
nsv8583	Chr.9:137303248 - 137322124 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	TPRN RNF224 NRARP ENTPD8 TMEM210 EXD3 NOXA1 TUBB4B TOR4A STPG3 SSNA1 GRIN1 FAM166A LRRC26 SLC34A3 TMEM203 RNF208 ANAPC2 C9orf173-AS1 MIR3621 NELFB NDOR1 CYSRT1
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	NRARP EXD3 TOR4A
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	TPRN LINC01451 C9orf172 ENTPD2 FBXW5 TMEM210 TUBB4B LCN8 DPP7 CLIC3 HSPC324 MAN1B1 GRIN1 CCDC183-AS1 ANAPC2 EDF1 NDOR1 MAMDC4 RNF224 C8G ABCA2 TMEM141 NPDC1 SAPCD2 MIR126 C9orf142 MIR4479 LRRC26 PRR31 SLC34A3 SNORA17B RNF208 C9orf173-AS1 LCNL1 LCN15 MIR3621 NELFB LOC100128593 LOC101930307 SNHG7 LCN6 LCN10 FAM69B SSNA1 LCN12 TMEM203 C9orf139 PTGDS CYSRT1 FUT7 TRAF2 PHPT1 NRARP EXD3 TOR4A STPG3 AGPAT2 UAP1L1 FAM166A CCDC183 MAN1B1-AS1 SNORA17A RABL6 MIR4292 EGFL7 MIR6722

More Information

Additional Information:

For this assay, SNP(s) [rs113267547] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding