Hs03754218_cn

• Gene Symbol: INPP5A
• Assay Reference Genome Location: Chr.10:132538673 on build GRCh38
• Cytoband: 10q26.3

Target Gene Details

• Entrez Gene ID: 3632
• Gene Name: inositol polyphosphate-5-phosphatase A
• Gene Aliases: 5PTASE
• Location: Chr.10:132537779-132783480 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
INPP5A	NM_005539.4			NP_005530.3
	XM_017016205.1			XP_016871694.1
	AF273055.1			AAM44458.1
	BC096280.2			AAH96280.1
	BC096281.2			AAH96281.1
	BC117515.1
	HY025461.1
	X77567.1			CAA54676.1
	Z31695.1			CAA83500.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509376	Chr.10:132473349 - 132584513 on Build GRCh38	Insertion	INPP5A LOC107984282
esv2759791	Chr.10:132412726 - 132613563 on Build GRCh38	Loss	PWWP2B INPP5A C10orf91 LOC107984282 LOC105378568
esv3624986	Chr.10:132322882 - 132551350 on Build GRCh38	Gain	LRRC27 PWWP2B STK32C INPP5A C10orf91 LOC107984282 LOC105378568
nsv1054934	Chr.10:130334322 - 133158679 on Build GRCh38	Gain	LINC01166 STK32C LINC01164 TCERG1L-AS1 C10orf91 LINC01167 LOC107984282 NKX6-2 LRRC27 PWWP2B CFAP46 BNIP3 DPYSL4 INPP5A ADGRA1 MIR378C PPP2R2D TCERG1L ADGRA1-AS1 LINC01168 LOC105378568 JAKMIP3
esv3624995	Chr.10:132503737 - 132548845 on Build GRCh38	Gain	INPP5A LOC107984282

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase

Gene Ontology Categories:

Process(es)

inositol phosphate metabolic process
phosphatidylinositol dephosphorylation

Function(s)

inositol-polyphosphate 5-phosphatase activity
protein binding
PH domain binding
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity