Hs03774071_cn

• Gene Symbol: ADAMTS8
• Assay Reference Genome Location: Chr.11:130409598 on build GRCh38
• Cytoband: 11q24.3

Target Gene Details

• Entrez Gene ID: 11095
• Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 8
• Gene Aliases: ADAM-TS8, METH2
• Location: Chr.11:130404923-130428993 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADAMTS8	NM_007037.5			NP_008968.4
	XM_017017145.1			XP_016872634.1
	AB209717.1			BAD92954.1
	AF060153.1			AAD48081.1
	AF175283.1			AAF25806.1
	AK123706.1
	BC089435.1			AAH89435.1
	BC113874.1			AAI13875.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759871	Chr.11:130099327 - 130472822 on Build GRCh38	Loss	ADAMTS15 ST14 ZBTB44 APLP2 LOC646383 ADAMTS8
nsv508660	Chr.11:130397628 - 130503590 on Build GRCh38	Deletion	ADAMTS15 LOC646383 ADAMTS8

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

metalloprotease

Gene Ontology Categories:

Process(es)

proteolysis
negative regulation of cell proliferation
phosphate ion transmembrane transport

Function(s)

metalloendopeptidase activity
integrin binding
heparin binding
metallopeptidase activity
zinc ion binding
low-affinity phosphate transmembrane transporter activity