Hs03793940_cn

• Gene Symbol: RASGRP2
• Assay Reference Genome Location: Chr.11:64743111 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 10235
• Gene Name: RAS guanyl releasing protein 2
• Gene Aliases: CALDAG-GEFI, CDC25L
• Location: Chr.11:64726911-64745456 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RASGRP2	NM_001098670.1			NP_001092140.1
	NM_001098671.1			NP_001092141.1
	NM_001318398.1			NP_001305327.1
	NM_153819.1			NP_722541.1
	XM_005273707.3			XP_005273764.3
	XM_011544718.1			XP_011543020.1
	XM_011544720.1			XP_011543022.1
	XM_011544721.1			XP_011543023.1
	XM_011544722.1			XP_011543024.1
	XM_011544723.2			XP_011543025.1
	XM_017017082.1	1	1064	XP_016872571.1
	XM_017017083.1	1	1064	XP_016872572.1
	XM_017017084.1			XP_016872573.1
	AF043722.1			AAF07219.1
	AF043723.1			AAF07220.1
	AF081194.1			AAC79698.1
	AK092882.1	1	679
	AK122694.1
	AK124023.1	1	1479
	BC110306.1			AAI10307.1
	BC117151.1
	DA286186.1
	DA529151.1
	DB498812.1
	U78170.1			AAD12741.1
	Y12336.1			CAA73005.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv528506	Chr.11:64577976 - 64933558 on Build GRCh38	Loss	MIR6749 SF1 PPP2R5B SLC22A12 NRXN2 MIR192 RASGRP2 ATG2A PYGM MEN1 CDC42BPG MIR194-2HG MAP4K2 EHD1 MIR6750 MIR194-2
dgv1965n54	Chr.11:64566642 - 64806117 on Build GRCh38	Loss	SF1 MAP4K2 SLC22A12 NRXN2 RASGRP2 SLC22A11 PYGM MEN1
dgv153n27	Chr.11:64709578 - 64817487 on Build GRCh38	Loss	SF1 MAP4K2 NRXN2 RASGRP2 PYGM MEN1
nsv832189	Chr.11:64719711 - 64852727 on Build GRCh38	Loss	SF1 MAP4K2 EHD1 NRXN2 RASGRP2 PYGM MEN1 CDC42BPG

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

regulation of cell growth
signal transduction
Ras protein signal transduction
positive regulation of GTPase activity
cellular response to calcium ion

Function(s)

guanyl-nucleotide exchange factor activity
calcium ion binding
lipid binding
diacylglycerol binding