Hs03905669_cn

• Gene Symbol: SCG5
• Assay Reference Genome Location: Chr.15:32645070 on build GRCh38
• Cytoband: 15q13.3

Target Gene Details

• Entrez Gene ID: 6447
• Gene Name: secretogranin V
• Gene Aliases: 7B2, P7B2, SGNE1, SgV
• Location: Chr.15:32641669-32697097 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SCG5	NM_001144757.1			NP_001138229.1
	NM_003020.3			NP_003011.1
	AK314965.1
	BC005349.1			AAH05349.1
	BC093053.1			AAH93053.1
	BP377248.1
	CR541824.1			CAG46623.1
	Y00757.1			CAA68726.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517740	Chr.15:31727863 - 32666510 on Build GRCh38	Gain+Loss	LOC101060588 GOLGA8O LOC101928042 LOC105370757 CHRNA7 LOC100996255 ULK4P1 LOC100653133 LOC105370940 GOLGA8K WHAMMP1 GOLGA8N SCG5 ARHGAP11A
nsv568913	Chr.15:32633875 - 33060788 on Build GRCh38	Gain	FMN1 LOC100131315 GREM1 LOC105370757 SCG5 ARHGAP11A
nsv428302	Chr.15:31646275 - 32694378 on Build GRCh38	Gain+Loss	LOC101060588 GOLGA8O OTUD7A LOC101928042 LOC105370757 CHRNA7 LOC100996255 ULK4P1 LOC100653133 LOC105370940 GOLGA8K WHAMMP1 GOLGA8N SCG5 ARHGAP11A
esv2760023	Chr.15:31474097 - 32694378 on Build GRCh38	Gain+Loss	LOC101060588 GOLGA8O OTUD7A LOC101928042 LOC105370757 CHRNA7 LOC100996255 ULK4P1 LOC100653133 LOC105370940 GOLGA8K WHAMMP1 GOLGA8N SCG5 ARHGAP11A
nsv1052620	Chr.15:32612402 - 34538731 on Build GRCh38	Gain	FMN1 LOC100131315 LOC101928134 MIR1233-2 KATNBL1 LOC101928042 LOC105370757 NUTM1 GOLGA8A TMCO5B SLC12A6 EMC7 PGBD4 GREM1 NOP10 CHRM5 SCG5 AVEN LPCAT4 GOLGA8B MIR1233-1 ARHGAP11A EMC4 RYR3
nsv483039	Chr.15:32574635 - 32751321 on Build GRCh38	Gain	LOC100131315 GREM1 GOLGA8N LOC101928042 LOC105370757 SCG5 LOC100996255 ARHGAP11A
esv33337	Chr.15:31689863 - 34575097 on Build GRCh38	Gain+Loss	LOC101060588 LOC100131315 LOC101928134 KATNBL1 LOC105370757 NUTM1 LOC100653133 SLC12A6 WHAMMP1 NOP10 GOLGA8N LPCAT4 MIR1233-1 ARHGAP11A EMC4 RYR3 FMN1 GOLGA8O MIR1233-2 LOC101928042 CHRNA7 LOC100996255 ULK4P1 GOLGA8A TMCO5B LOC105370940 GOLGA8K EMC7 PGBD4 GREM1 CHRM5 SCG5 AVEN GOLGA8B
esv3892661	Chr.15:32393132 - 32776080 on Build GRCh38	Gain	LOC101060588 FMN1 LOC100131315 GOLGA8O LOC101928042 LOC105370757 LOC100996255 ULK4P1 LOC100653133 GOLGA8K WHAMMP1 GREM1 GOLGA8N SCG5 ARHGAP11A
nsv469587	Chr.15:32529739 - 32694378 on Build GRCh38	Loss	WHAMMP1 GOLGA8N LOC101928042 LOC105370757 SCG5 LOC100996255 ARHGAP11A
esv2422296	Chr.15:32506737 - 32929014 on Build GRCh38	Duplication	FMN1 LOC100131315 WHAMMP1 GREM1 GOLGA8N LOC101928042 LOC105370757 SCG5 LOC100996255 ARHGAP11A
dgv4456n54	Chr.15:32604149 - 34557061 on Build GRCh38	Gain	LOC100131315 LOC101928134 KATNBL1 LOC105370757 NUTM1 SLC12A6 NOP10 GOLGA8N LPCAT4 MIR1233-1 ARHGAP11A EMC4 RYR3 FMN1 MIR1233-2 LOC101928042 GOLGA8A TMCO5B EMC7 PGBD4 GREM1 CHRM5 SCG5 AVEN GOLGA8B

More Information

Additional Information:

For this assay, SNP(s) [rs72715243] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

intracellular protein transport
neuropeptide signaling pathway
peptide hormone processing
negative regulation of catalytic activity
regulation of hormone secretion

Function(s)

enzyme inhibitor activity
protein binding
GTP binding
unfolded protein binding