Hs03933826_cn

• Gene Symbol: CBFA2T3
• Assay Reference Genome Location: Chr.16:88929209 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 863
• Gene Name: CBFA2/RUNX1 translocation partner 3
• Gene Aliases: ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
• Location: Chr.16:88874855-88977198 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBFA2T3	NM_005187.5			NP_005178.4
	NM_175931.2			NP_787127.1
	XM_005256323.4			XP_005256380.1
	XM_011523419.2			XP_011521721.1
	XM_017023811.1			XP_016879300.1
	AB010419.1			BAA29061.1
	AB010420.1			BAA29062.1
	AK308355.1
	AK314766.1
	BC047019.1
	BC062624.1			AAH62624.1
	BE676580.1
	BP282804.1

Target Gene Details

• Entrez Gene ID: 105371409
• Gene Name: uncharacterized LOC105371409
• Gene Aliases: -
• Location: Chr.16:88929150-88930663 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105371409	XM_017023971.1	1	60	XP_016879460.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	PIEZO1 LOC105371409 CDT1 LOC107987238 CBFA2T3 TRAPPC2L PABPN1L LOC100129697 APRT LOC101927793 GALNS
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LOC400558 PIEZO1 ZNF778 CDH15 LOC339059 CTU2 LOC107987238 ACSF3 LOC101927793 LINC00304 LOC100289580 LOC105371409 CDT1 CBFA2T3 TRAPPC2L PABPN1L SLC22A31 MIR4722 LOC100129697 APRT GALNS
nsv1066077	Chr.16:88916836 - 89035141 on Build GRCh38	Gain	LOC105371409 CBFA2T3 LOC100129697
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC400558 CDH15 LOC107987238 ACSF3 LOC101927793 LINC00304 LOC105371409 CDT1 CBFA2T3 TRAPPC2L PABPN1L SLC22A31 LOC100129697 APRT GALNS
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LOC400558 LOC105371414 PIEZO1 ZNF778 CDH15 LOC339059 LOC107987238 ANKRD11 ACSF3 LOC101927793 LINC00304 LOC100289580 LOC105371409 CDT1 CBFA2T3 TRAPPC2L PABPN1L SLC22A31 LOC100287036 LOC100129697 APRT GALNS
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC105371409 CDT1 LOC107987238 CBFA2T3 TRAPPC2L PABPN1L LOC100129697 APRT LOC101927793 GALNS
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	LOC400558 CDH15 LOC107987238 ACSF3 LOC101927793 LINC00304 LOC105371409 CDT1 CBFA2T3 TRAPPC2L PABPN1L LOC100129697 APRT GALNS
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	PIEZO1 ZNF778 SNORD68 VPS9D1-AS1 FANCA LINC00304 FAM157C CDT1 CPNE7 SPIRE2 CTU2 DBNDD1 ANKRD11 CYBA PRDM7 VPS9D1 LOC100289580 SPG7 SLC22A31 IL17C SNAI3-AS1 URAHP LOC400558 LOC339059 DEF8 TUBB8P7 SNAI3 MVD TCF25 SPATA2L PABPN1L MIR4722 AFG3L1P GAS8-AS1 RNF166 APRT SPATA33 LOC105371414 CDH15 LOC101927817 MC1R LOC105371419 TUBB3 LOC107987238 RPL13 LOC107984817 ACSF3 LOC101927793 CENPBD1 ZNF276 DPEP1 CHMP1A GAS8 LOC105371409 CBFA2T3 TRAPPC2L LOC100287036 CDK10 LOC100129697 GALNS
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	PIEZO1 LOC339059 CTU2 LOC107987238 LOC101927793 LOC100289580 LOC105371409 CDT1 CBFA2T3 TRAPPC2L PABPN1L MIR4722 LOC100129697 APRT GALNS

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding