Hs03933826_cn

• Gene Symbol: CBFA2T3
• Assay Reference Genome Location: Chr.16:88929209 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 863
• Gene Name: CBFA2/RUNX1 translocation partner 3
• Gene Aliases: ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4
• Location: Chr.16:88874855-88977198 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CBFA2T3	NM_005187.5			NP_005178.4
	NM_175931.2			NP_787127.1
	XM_005256323.4			XP_005256380.1
	XM_011523419.2			XP_011521721.1
	XM_017023811.1			XP_016879300.1
	AB010419.1			BAA29061.1
	AB010420.1			BAA29062.1
	AK308355.1
	AK314766.1
	BC047019.1
	BC062624.1			AAH62624.1
	BE676580.1
	BP282804.1

Target Gene Details

• Entrez Gene ID: 105371409
• Gene Name: uncharacterized LOC105371409
• Gene Aliases: -
• Location: Chr.16:88929150-88930663 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105371409	XM_017023971.1	1	60	XP_016879460.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	CBFA2T3 LOC105371409 LOC100129697 PABPN1L LOC107987238 TRAPPC2L GALNS CDT1 PIEZO1 APRT LOC101927793
nsv1066077	Chr.16:88916836 - 89035141 on Build GRCh38	Gain	CBFA2T3 LOC105371409 LOC100129697
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LINC00304 CDH15 CBFA2T3 MIR4722 LOC100129697 CTU2 TRAPPC2L APRT ACSF3 LOC105371409 LOC400558 PABPN1L LOC107987238 SLC22A31 GALNS ZNF778 CDT1 PIEZO1 LOC101927793 LOC339059 LOC100289580
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LINC00304 CDH15 CBFA2T3 LOC100129697 TRAPPC2L APRT ACSF3 LOC105371409 LOC400558 PABPN1L LOC107987238 SLC22A31 GALNS CDT1 LOC101927793
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	LINC00304 CDH15 CBFA2T3 LOC100287036 LOC100129697 TRAPPC2L ANKRD11 APRT ACSF3 LOC105371414 LOC105371409 LOC400558 PABPN1L LOC107987238 SLC22A31 GALNS ZNF778 CDT1 PIEZO1 LOC101927793 LOC339059 LOC100289580
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	LINC00304 CDH15 CBFA2T3 LOC100129697 TRAPPC2L APRT ACSF3 LOC105371409 LOC400558 PABPN1L LOC107987238 GALNS CDT1 LOC101927793
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	CBFA2T3 LOC105371409 LOC100129697 PABPN1L LOC107987238 TRAPPC2L GALNS CDT1 APRT LOC101927793
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC100129697 SPIRE2 GAS8 SNORD68 TUBB8P7 SPATA33 VPS9D1-AS1 LOC400558 PABPN1L CHMP1A FANCA ZNF778 MVD AFG3L1P LINC00304 CBFA2T3 SPATA2L RPL13 TCF25 PRDM7 LOC107984817 TUBB3 CENPBD1 SLC22A31 URAHP PIEZO1 LOC339059 CDH15 LOC105371419 ZNF276 MIR4722 SPG7 RNF166 CTU2 TRAPPC2L ANKRD11 APRT CPNE7 SNAI3-AS1 IL17C LOC105371409 SNAI3 GALNS CDT1 VPS9D1 FAM157C DBNDD1 LOC101927793 LOC100289580 DPEP1 LOC100287036 ACSF3 LOC105371414 GAS8-AS1 DEF8 LOC107987238 MC1R CYBA CDK10 LOC101927817
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	CBFA2T3 MIR4722 LOC100129697 CTU2 TRAPPC2L APRT LOC105371409 PABPN1L LOC107987238 GALNS CDT1 PIEZO1 LOC101927793 LOC339059 LOC100289580

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

transcription cofactor

Gene Ontology Categories:

Process(es)

response to hypoxia
transcription, DNA-templated
cell proliferation
negative regulation of cell proliferation
granulocyte differentiation
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of glycolytic process
negative regulation of transcription, DNA-templated
regulation of aerobic respiration

Function(s)

transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
metal ion binding