Hs03934396_cn

• Gene Symbol: CTU2
• Assay Reference Genome Location: Chr.16:88708458 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 348180
• Gene Name: cytosolic thiouridylase subunit 2
• Gene Aliases: C16orf84, NCS2, UPF0432
• Location: Chr.16:88706463-88715386 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTU2	NM_001012759.2			NP_001012777.1
	NM_001012762.2			NP_001012780.1
	NM_001318507.1			NP_001305436.1
	NM_001318513.1			NP_001305442.1
	BC080540.1			AAH80540.1
	BC108659.1			AAI08660.1
	BC121805.1
	BC125269.1
	BC157881.1
	BI520274.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CDT1 LOC107987238 APRT CDH15 LOC105371409 ACSF3 TRAPPC2L CBFA2T3 CTU2 ZNF778 LOC339059 MIR4722 PIEZO1 LOC101927793 PABPN1L GALNS SLC22A31 LOC100289580 LOC400558 LOC100129697 LINC00304
nsv471113	Chr.16:88650665 - 88764428 on Build GRCh38	Loss	MIR4722 MVD PIEZO1 RNF166 SNAI3-AS1 LOC100289580 CTU2 SNAI3 LOC339059 CYBA
nsv471114	Chr.16:88688461 - 88756339 on Build GRCh38	Gain	MIR4722 PIEZO1 RNF166 LOC100289580 CTU2 LOC339059
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	CDT1 MIR4722 LOC107987238 APRT PIEZO1 RNF166 GALNS SNAI3-AS1 LOC100289580 CTU2 SNAI3 LOC339059
nsv1065973	Chr.16:88661146 - 88731220 on Build GRCh38	Loss	MIR4722 MVD PIEZO1 RNF166 SNAI3-AS1 LOC100289580 CTU2 SNAI3
nsv833327	Chr.16:88667431 - 88757621 on Build GRCh38	Loss	MIR4722 PIEZO1 RNF166 SNAI3-AS1 LOC100289580 CTU2 SNAI3 LOC339059
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	ZFPM1 IL17C ZC3H18 CTU2 LOC107984862 SNAI3 LOC339059 CYBA MIR4722 ZC3H18-AS1 MVD PIEZO1 RNF166 SNAI3-AS1 LOC100289580 ZNF469 MIR5189
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC100287036 APRT MC1R LOC105371409 CENPBD1 CHMP1A SPIRE2 RPL13 TRAPPC2L CBFA2T3 SPG7 CTU2 PRDM7 TCF25 GAS8 LOC400558 LOC100129697 LINC00304 CDT1 TUBB8P7 SNAI3 LOC339059 CYBA MVD SPATA33 SPATA2L VPS9D1-AS1 SLC22A31 URAHP LOC107987238 ANKRD11 FANCA DPEP1 CPNE7 MIR4722 AFG3L1P LOC101927793 PABPN1L FAM157C RNF166 LOC105371414 VPS9D1 LOC100289580 LOC101927817 GAS8-AS1 TUBB3 CDK10 ZNF276 DBNDD1 CDH15 LOC105371419 IL17C ACSF3 DEF8 ZNF778 SNORD68 LOC107984817 PIEZO1 GALNS SNAI3-AS1
nsv1160442	Chr.16:88708161 - 88778524 on Build GRCh38	Deletion	MIR4722 PIEZO1 LOC100289580 CTU2 LOC339059

More Information

Additional Information:

For this assay, SNP(s) [rs115942789] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA processing factor, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

tRNA wobble uridine modification
tRNA modification
protein urmylation
tRNA thio-modification

Function(s)

tRNA binding
protein binding
nucleotidyltransferase activity