Hs03934396_cn

• Gene Symbol: CTU2
• Assay Reference Genome Location: Chr.16:88708458 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 348180
• Gene Name: cytosolic thiouridylase subunit 2
• Gene Aliases: C16orf84, NCS2, UPF0432
• Location: Chr.16:88706463-88715386 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CTU2	NM_001012759.2			NP_001012777.1
	NM_001012762.2			NP_001012780.1
	NM_001318507.1			NP_001305436.1
	NM_001318513.1			NP_001305442.1
	BC080540.1			AAH80540.1
	BC108659.1			AAI08660.1
	BC121805.1
	BC125269.1
	BC157881.1
	BI520274.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	LINC00304 LOC107987238 LOC400558 GALNS LOC101927793 MIR4722 LOC100289580 CTU2 CBFA2T3 SLC22A31 PIEZO1 CDH15 TRAPPC2L LOC105371409 PABPN1L APRT LOC100129697 ACSF3 ZNF778 CDT1 LOC339059
nsv471114	Chr.16:88688461 - 88756339 on Build GRCh38	Gain	MIR4722 LOC100289580 CTU2 RNF166 PIEZO1 LOC339059
nsv471113	Chr.16:88650665 - 88764428 on Build GRCh38	Loss	SNAI3-AS1 MIR4722 LOC100289580 CTU2 CYBA RNF166 PIEZO1 SNAI3 MVD LOC339059
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	LOC107987238 GALNS SNAI3-AS1 MIR4722 LOC100289580 CTU2 RNF166 PIEZO1 SNAI3 CDT1 LOC339059 APRT
nsv1065973	Chr.16:88661146 - 88731220 on Build GRCh38	Loss	SNAI3-AS1 MIR4722 LOC100289580 CTU2 RNF166 PIEZO1 SNAI3 MVD
nsv833327	Chr.16:88667431 - 88757621 on Build GRCh38	Loss	SNAI3-AS1 MIR4722 LOC100289580 CTU2 RNF166 PIEZO1 SNAI3 LOC339059
nsv952070	Chr.16:88257295 - 88780192 on Build GRCh38	Deletion	MIR5189 SNAI3-AS1 ZC3H18-AS1 MIR4722 LOC100289580 CTU2 CYBA RNF166 ZC3H18 PIEZO1 ZNF469 SNAI3 MVD LOC339059 LOC107984862 IL17C ZFPM1
nsv1160442	Chr.16:88708161 - 88778524 on Build GRCh38	Deletion	MIR4722 LOC100289580 CTU2 PIEZO1 LOC339059
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	GAS8 DPEP1 LOC101927793 MIR4722 LOC100289580 SPG7 LOC105371409 LOC100129697 TUBB8P7 GAS8-AS1 SPATA2L LOC107984817 SPATA33 ZNF276 LOC100287036 IL17C CPNE7 LINC00304 DEF8 LOC107987238 CTU2 CDK10 RNF166 VPS9D1 LOC105371419 PIEZO1 DBNDD1 TCF25 APRT PRDM7 SNAI3 MVD SPIRE2 AFG3L1P LOC400558 SNAI3-AS1 LOC101927817 CYBA TUBB3 SLC22A31 CDH15 TRAPPC2L FAM157C LOC105371414 RPL13 ACSF3 ANKRD11 MC1R CDT1 LOC339059 CHMP1A GALNS FANCA CBFA2T3 PABPN1L ZNF778 VPS9D1-AS1 CENPBD1 URAHP SNORD68

More Information

Additional Information:

For this assay, SNP(s) [rs115942789] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein, RNA processing factor, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

tRNA wobble uridine modification
tRNA modification
protein urmylation
tRNA thio-modification

Function(s)

tRNA binding
protein binding
nucleotidyltransferase activity