Hs03940439_cn

• Gene Symbol: RAB11FIP3
• Assay Reference Genome Location: Chr.16:457224 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 9727
• Gene Name: RAB11 family interacting protein 3
• Gene Aliases: CART1, Rab11-FIP3
• Location: Chr.16:425621-522485 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RAB11FIP3	NM_014700.3			NP_055515.1
	XM_005255713.3			XP_005255770.1
	XM_005255717.3			XP_005255774.1
	XM_005255718.3			XP_005255775.1
	XM_017023907.1			XP_016879396.1
	AB014565.1
	AF395731.1			AAL12940.1
	BC051360.1			AAH51360.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	TMEM204 LINC00254 BRICD5 SNORA10 JMJD8 MIR3176 AMDHD2 PGP CEMP1 NPRL3 WDR90 CCNF FBXL16 SSTR5 TBC1D24 LOC106660606 ERVK13-1 PRSS29P C1QTNF8 RAB11FIP3 RHOT2 TBL3 SOX8 TELO2 MRPS34 LOC101929280 MIR3180-5 LINC00235 HAGH SNRNP25 LOC105371049 TSC2 HBM NDUFB10 LOC100134368 HBA1 ABCA17P SNHG9 CCDC78 LOC105371045 MIR6767 TMEM8A PIGQ LOC105371184 NPW MEIOB WDR24 WASIR2 RHBDL1 E4F1 RPL23AP5 FLJ42627 ATP6V0C DECR2 NUBP2 CRAMP1 MCRIP2 NTHL1 RAB40C PRR35 RGS11 SLC9A3R2 SNORD60 POLR3K ECI1 PRSS27 NME4 TPSD1 TPSAB1 NOXO1 NTN3 RHBDF1 DNASE1L2 HBA2 SNHG19 CASKIN1 IFT140 ABCA3 RAB26 EME2 HN1L CAPN15 IGFALS MRPL28 RPS2 HS3ST6 GNG13 MIR3177 UBE2I RNF151 HAGHL AXIN1 LOC652276 HBZ MIR4717 MIR1225 TPSB2 TRAF7 LOC729652 LOC107984876 WFIKKN1 SSTR5-AS1 NME3 ARHGDIG LOC105371047 PRR25 MIR940 MSLN MSRB1 SPSB3 MAPK8IP3 LOC105371046 PTX4 MIR662 CCDC154 UNKL FAHD1 RNPS1 FAM173A KCTD5 SNORA64 NARFL MIR3178 TPSG1 CACNA1H LOC105371038 NHLRC4 PDPK1 CLCN7 CHTF18 METRN MIR4516 C16orf59 METTL26 MIR5587 STUB1 LOC107987233 MIR6859-4 LMF1-AS1 ZNF598 LMF1 LOC100287175 FAM234A GNPTG PKD1 HBQ1 RPL3L C16orf91 LUC7L MIR3677 DDX11L10 GFER RPUSD1 MIR6511B1 SYNGR3 MLST8 BAIAP3 MIR6768 SNORA78 TSR3 MPG PDIA2
esv3637576	Chr.16:439034 - 480097 on Build GRCh38	Gain	RAB11FIP3
esv3637563	Chr.16:263248 - 505590 on Build GRCh38	Gain	AXIN1 ARHGDIG RPL23AP5 RAB11FIP3 RGS11 PDIA2 TMEM8A FAM234A DECR2 NME4 MRPL28 LOC100134368
nsv526903	Chr.16:451362 - 810673 on Build GRCh38	Loss	LOC105371038 NHLRC4 CAPN15 CCDC78 CHTF18 METRN PIGQ METTL26 LOC105371184 GNG13 WDR24 HAGHL MIR5587 JMJD8 MIR3176 STUB1 RHBDL1 LOC107987233 LOC100287175 WDR90 FBXL16 WFIKKN1 MCRIP2 RAB40C PRR35 RAB11FIP3 RHOT2 RPUSD1 PRR25 MSLN LOC101929280 LINC00235 MIR662 FAM173A NARFL
nsv570954	Chr.16:342461 - 530124 on Build GRCh38	Loss	LINC00235 AXIN1 RPL23AP5 RAB11FIP3 CAPN15 TMEM8A DECR2 NME4 MRPL28 LOC100134368
esv1003529	Chr.16:455611 - 459074 on Build GRCh38	Insertion	RAB11FIP3
dgv32n68	Chr.16:245507 - 476226 on Build GRCh38	Loss	AXIN1 ARHGDIG RPL23AP5 RAB11FIP3 RGS11 PDIA2 TMEM8A FAM234A DECR2 NME4 MRPL28 LOC100134368

More Information

Additional Information:

For this assay, SNP(s) [rs76662672] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cytokinesis
vesicle-mediated transport
endocytic recycling
protein localization to cilium
negative regulation of adiponectin secretion

Function(s)

calcium ion binding
protein binding
Rab GTPase binding
ADP-ribosylation factor binding
protein homodimerization activity
dynein light intermediate chain binding