Hs03941047_cn

• Gene Symbol: POLR3K
• Assay Reference Genome Location: Chr.16:50379 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 51728
• Gene Name: RNA polymerase III subunit K
• Gene Aliases: C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5
• Location: Chr.16:46979-53632 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3K	NM_016310.4			NP_057394.3
	AF051316.1			AAF18268.1
	AF060223.1			AAG43123.1
	BC011932.2			AAH11932.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv518291	Chr.16:47354 - 254515 on Build GRCh38	Loss	HBQ1 HBA1 LUC7L HBM HBA2 POLR3K HBZ FAM234A MPG SNRNP25 RHBDF1 NPRL3
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	FAM173A SNORA10 PRR35 BAIAP3 TMEM8A WFIKKN1 LOC107987233 KCTD5 PDPK1 SYNGR3 LINC00254 CLCN7 POLR3K HBZ C1QTNF8 MIR662 LOC100134368 FLJ42627 MEIOB RGS11 PGP MCRIP2 LMF1-AS1 SPSB3 RAB40C MIR5587 LOC105371045 LOC107984876 HN1L HBA1 TPSG1 MSRB1 RNPS1 LOC729652 GNG13 GFER STUB1 MAPK8IP3 NTHL1 MRPS34 RPS2 JMJD8 LOC105371046 LUC7L ATP6V0C RAB11FIP3 HBA2 TPSD1 NUBP2 MRPL28 TSC2 NPW TRAF7 TELO2 AXIN1 WDR90 LOC106660606 HAGH CACNA1H E4F1 PRR25 LOC105371038 WASIR2 PTX4 TBC1D24 CRAMP1 MIR940 LMF1 FAM234A UBE2I SSTR5 PIGQ TMEM204 CASKIN1 SSTR5-AS1 MIR4516 PRSS27 HBM ABCA17P TPSB2 SNORA64 NARFL NOXO1 TSR3 MIR4717 CCNF IGFALS ABCA3 C16orf91 HS3ST6 MPG ARHGDIG NPRL3 DECR2 CHTF18 MIR6767 RPL3L LINC00235 PRSS29P LOC101929280 AMDHD2 CAPN15 NDUFB10 IFT140 HBQ1 NME3 MIR3180-5 NME4 SNORA78 LOC100287175 MIR6511B1 PDIA2 CCDC154 MIR3677 METTL26 DDX11L10 RHBDF1 METRN MIR1225 SNHG19 LOC105371184 RHOT2 MIR3177 ERVK13-1 SNHG9 CEMP1 GNPTG TBL3 SLC9A3R2 C16orf59 MIR6768 BRICD5 RPUSD1 EME2 FBXL16 WDR24 LOC105371047 DNASE1L2 FAHD1 HAGHL RHBDL1 RAB26 SNRNP25 NHLRC4 LOC105371049 ECI1 RPL23AP5 MIR3176 NTN3 TPSAB1 ZNF598 MLST8 UNKL MSLN SNORD60 SOX8 RNF151 PKD1 MIR6859-4 CCDC78 LOC652276 MIR3178
nsv1044732	Chr.16:35815 - 60707 on Build GRCh38	Loss	POLR3K SNRNP25 RHBDF1
dgv2688n100	Chr.16:10765 - 80854 on Build GRCh38	Gain	POLR3K MIR6859-4 MPG SNRNP25 WASIR2 DDX11L10 RHBDF1
esv2760065	Chr.16:31052 - 143601 on Build GRCh38	Gain	POLR3K HBZ MPG SNRNP25 RHBDF1 NPRL3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase III promoter
termination of RNA polymerase III transcription
positive regulation of type I interferon production
innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
nucleic acid binding
DNA-directed RNA polymerase activity
zinc ion binding