Hs03941047_cn

• Gene Symbol: POLR3K
• Assay Reference Genome Location: Chr.16:50379 on build GRCh38
• Cytoband: 16p13.3

Target Gene Details

• Entrez Gene ID: 51728
• Gene Name: RNA polymerase III subunit K
• Gene Aliases: C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5
• Location: Chr.16:46979-53632 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3K	NM_016310.4			NP_057394.3
	AF051316.1			AAF18268.1
	AF060223.1			AAG43123.1
	BC011932.2			AAH11932.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv522688	Chr.16:47354 - 55444 on Build GRCh38	Loss	SNRNP25 POLR3K
esv2422427	Chr.16:10001 - 2723164 on Build GRCh38	Duplication	JMJD8 E4F1 RPL23AP5 WDR90 TPSB2 SNHG9 CACNA1H FAM234A ARHGDIG CCDC154 CEMP1 MSRB1 SNORA78 RNF151 HAGH PRSS29P CLCN7 RAB40C LOC105371038 MIR4717 METTL26 AXIN1 LMF1 MIR3677 FLJ42627 LOC105371046 NUBP2 LOC729652 RHOT2 LOC107987233 ABCA17P CCDC78 NME3 AMDHD2 C16orf59 WDR24 STUB1 HBM WFIKKN1 LOC105371047 RPUSD1 NHLRC4 ERVK13-1 NME4 SSTR5-AS1 PIGQ MIR4516 HBA1 DNASE1L2 LOC107984876 ABCA3 MEIOB TSR3 MCRIP2 C1QTNF8 TELO2 RHBDF1 GNG13 HBA2 TMEM8A PKD1 MRPL28 LOC105371045 LOC652276 DDX11L10 TRAF7 MLST8 UBE2I MIR5587 EME2 C16orf91 HS3ST6 BAIAP3 SLC9A3R2 ATP6V0C PDIA2 RAB26 SNORA64 MSLN PRR35 DECR2 FBXL16 UNKL SOX8 RPS2 SNRNP25 NTHL1 NARFL CHTF18 ZNF598 ECI1 LOC100134368 LOC105371049 MIR6511B1 LMF1-AS1 LINC00254 POLR3K SNHG19 TMEM204 IFT140 NOXO1 RPL3L TPSAB1 HBQ1 MIR662 SYNGR3 TSC2 MIR6767 MRPS34 SSTR5 LUC7L IGFALS LOC106660606 FAM173A SNORD60 PTX4 NPRL3 MIR1225 HAGHL GFER TPSG1 MIR6859-4 RHBDL1 TBC1D24 RGS11 HBZ CCNF SPSB3 MIR3180-5 PRSS27 GNPTG CAPN15 LINC00235 WASIR2 NPW TPSD1 BRICD5 SNORA10 PRR25 RAB11FIP3 MPG MIR3178 RNPS1 PGP KCTD5 MIR6768 NDUFB10 LOC101929280 LOC100287175 MIR3177 CRAMP1 MIR3176 CASKIN1 PDPK1 HN1L TBL3 MAPK8IP3 METRN LOC105371184 NTN3 FAHD1 MIR940
nsv1044732	Chr.16:35815 - 60707 on Build GRCh38	Loss	RHBDF1 SNRNP25 POLR3K
dgv2690n100	Chr.16:10765 - 207261 on Build GRCh38	Gain	LUC7L HBZ HBA1 POLR3K WASIR2 NPRL3 HBQ1 RHBDF1 HBA2 MPG HBM SNRNP25 DDX11L10 MIR6859-4
esv2760065	Chr.16:31052 - 143601 on Build GRCh38	Gain	HBZ NPRL3 RHBDF1 MPG SNRNP25 POLR3K

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

transcription from RNA polymerase III promoter
termination of RNA polymerase III transcription
positive regulation of type I interferon production
innate immune response
defense response to virus

Function(s)

RNA polymerase III activity
nucleic acid binding
DNA-directed RNA polymerase activity
zinc ion binding