Hs04014919_cn

• Gene Symbol: CASP14
• Assay Reference Genome Location: Chr.19:15058228 on build GRCh38
• Cytoband: 19p13.12

Target Gene Details

• Entrez Gene ID: 23581
• Gene Name: caspase 14
• Gene Aliases: -
• Location: Chr.19:15049480-15058293 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CASP14	NM_012114.2	7	3080	NP_036246.1
	BM840054.1	1	212
	EU502748.1	7	3176

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv654e214	Chr.19:15050284 - 15101244 on Build GRCh38	Gain	OR1I1 CASP14
esv3643762	Chr.19:15052933 - 15067870 on Build GRCh38	Gain	CASP14
esv2758746	Chr.19:14986138 - 15148368 on Build GRCh38	Gain	ILVBL OR1I1 CASP14 CCDC105 SYDE1 SLC1A6

More Information

Additional Information:

For this assay, SNP(s) [rs76111697,rs77468598] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

proteolysis
apoptotic process
epidermis development
keratinization
cornification

Function(s)

cysteine-type endopeptidase activity
protein binding
cysteine-type endopeptidase activity involved in apoptotic process