Hs04018440_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1067003 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	AK300341.1
	DC382305.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	ABCA7 CIRBP-AS1 GPX4 LOC102725180 MIDN CBARP CIRBP STK11 EFNA2 C19orf24 POLR2E ARHGAP45 ATP5D SBNO2
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	ABCA7 CIRBP-AS1 GPX4 GRIN3B RNU6-9 LOC105372235 RNU6-2 LOC102725180 MIDN KISS1R CBARP CIRBP STK11 EFNA2 C19orf24 CNN2 POLR2E TMEM259 ARHGAP45 ATP5D ARID3A WDR18 R3HDM4 SBNO2
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	ABCA7 CIRBP-AS1 GPX4 LOC102725180 MIDN CBARP CIRBP STK11 EFNA2 C19orf24 CNN2 POLR2E ARHGAP45 ATP5D SBNO2
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	ABCA7 CIRBP-AS1 GPX4 LOC105372235 RNU6-2 LOC102725180 MED16 KISS1R STK11 EFNA2 C19orf24 POLR2E TMEM259 ATP5D ARID3A SBNO2 GRIN3B RNU6-9 MIDN CBARP CIRBP CNN2 ARHGAP45 WDR18 R3HDM4
esv3643383	Chr.19:1012555 - 1069137 on Build GRCh38	Gain	CNN2 ABCA7 RNU6-2 TMEM259 ARHGAP45
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	POLR2E ABCA7 GPX4 ARHGAP45 SBNO2
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	CNN2 POLR2E ABCA7 GPX4 GRIN3B LOC105372235 RNU6-2 TMEM259 ARHGAP45 ARID3A WDR18 SBNO2
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	CNN2 POLR2E ABCA7 GPX4 GRIN3B LOC105372235 RNU6-2 TMEM259 ARHGAP45 ARID3A WDR18 SBNO2
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	PALM ABCA7 MISP GPX4 LOC105372235 RNU6-2 FGF22 MED16 KISS1R MADCAM1 POLR2E PRSS57 FSTL3 BSG C2CD4C TMEM259 ARID3A AZU1 PRTN3 GRIN3B RNU6-9 SHC2 LOC101928450 MIR3187 TPGS1 HCN2 POLRMT CNN2 GZMM CFD RNF126 MIR4745 ODF3L2 CDC34 ELANE ARHGAP45 PTBP1 THEG WDR18 PLPPR3 R3HDM4
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	CNN2 POLR2E ABCA7 GPX4 RNU6-2 TMEM259 ARHGAP45 SBNO2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding