Hs04022630_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1066660 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	AK300341.1
	DC382305.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	CIRBP-AS1 STK11 ATP5D CIRBP ARHGAP45 GPX4 LOC102725180 POLR2E SBNO2 MIDN EFNA2 ABCA7 CBARP C19orf24
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	CIRBP-AS1 STK11 R3HDM4 LOC105372235 ATP5D CIRBP ARHGAP45 WDR18 CNN2 GPX4 LOC102725180 POLR2E RNU6-2 SBNO2 MIDN RNU6-9 EFNA2 ABCA7 CBARP ARID3A C19orf24 GRIN3B KISS1R TMEM259
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	CIRBP-AS1 STK11 ATP5D CIRBP ARHGAP45 CNN2 GPX4 LOC102725180 POLR2E SBNO2 MIDN EFNA2 ABCA7 CBARP C19orf24
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	R3HDM4 ATP5D CIRBP CNN2 GPX4 LOC102725180 RNU6-2 SBNO2 CBARP C19orf24 MED16 GRIN3B TMEM259 CIRBP-AS1 STK11 LOC105372235 ARHGAP45 WDR18 POLR2E MIDN RNU6-9 EFNA2 ABCA7 ARID3A KISS1R
esv3643383	Chr.19:1012555 - 1069137 on Build GRCh38	Gain	ABCA7 ARHGAP45 CNN2 RNU6-2 TMEM259
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	ABCA7 ARHGAP45 GPX4 POLR2E SBNO2
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	LOC105372235 ABCA7 ARHGAP45 WDR18 CNN2 ARID3A GPX4 POLR2E GRIN3B RNU6-2 SBNO2 TMEM259
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	LOC105372235 ABCA7 ARHGAP45 WDR18 CNN2 ARID3A GPX4 POLR2E GRIN3B RNU6-2 SBNO2 TMEM259
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	R3HDM4 CNN2 PRTN3 PRSS57 GPX4 PTBP1 TPGS1 GZMM C2CD4C RNU6-2 MIR4745 MIR3187 MED16 THEG FGF22 POLRMT GRIN3B TMEM259 LOC105372235 ARHGAP45 WDR18 ELANE POLR2E CFD MADCAM1 RNF126 CDC34 RNU6-9 ABCA7 ARID3A PLPPR3 LOC101928450 SHC2 ODF3L2 FSTL3 AZU1 MISP HCN2 KISS1R BSG PALM
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	ABCA7 ARHGAP45 CNN2 GPX4 POLR2E RNU6-2 SBNO2 TMEM259

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding