Hs04024589_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1071133 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	NM_001321232.1			NP_001308161.1
	NM_012292.4			NP_036424.2
	XM_006722713.1			XP_006722776.1
	XM_011527858.1			XP_011526160.1
	AK300341.1
	AK304271.1
	AK304765.1
	BC035564.1			AAH35564.1
	BC065223.1			AAH65223.1
	D86976.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	EFNA2 CIRBP CIRBP-AS1 C19orf24 GPX4 MIDN ATP5D SBNO2 STK11 POLR2E ARHGAP45 CBARP LOC102725180 ABCA7
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	EFNA2 CIRBP R3HDM4 CIRBP-AS1 LOC105372235 C19orf24 GPX4 MIDN ATP5D KISS1R SBNO2 WDR18 STK11 CNN2 POLR2E ARID3A RNU6-9 RNU6-2 ARHGAP45 CBARP LOC102725180 ABCA7 TMEM259 GRIN3B
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	EFNA2 CIRBP CIRBP-AS1 C19orf24 GPX4 MIDN ATP5D SBNO2 STK11 CNN2 POLR2E ARHGAP45 CBARP LOC102725180 ABCA7
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	MED16 R3HDM4 CIRBP-AS1 LOC105372235 C19orf24 MIDN SBNO2 WDR18 STK11 ARID3A RNU6-9 RNU6-2 ARHGAP45 LOC102725180 GRIN3B EFNA2 CIRBP GPX4 ATP5D KISS1R CNN2 POLR2E CBARP ABCA7 TMEM259
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	SBNO2 POLR2E GPX4 ARHGAP45 ABCA7
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	SBNO2 WDR18 LOC105372235 CNN2 POLR2E ARID3A GPX4 RNU6-2 ARHGAP45 ABCA7 TMEM259 GRIN3B
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	SBNO2 WDR18 LOC105372235 CNN2 POLR2E ARID3A GPX4 RNU6-2 ARHGAP45 ABCA7 TMEM259 GRIN3B
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	MED16 R3HDM4 LOC105372235 GZMM PALM LOC101928450 BSG MIR4745 ELANE C2CD4C WDR18 ODF3L2 MISP CDC34 CFD FGF22 ARID3A RNU6-9 RNU6-2 ARHGAP45 GRIN3B FSTL3 MADCAM1 PRSS57 PRTN3 RNF126 SHC2 GPX4 TPGS1 KISS1R THEG PTBP1 CNN2 POLR2E HCN2 AZU1 PLPPR3 POLRMT ABCA7 TMEM259 MIR3187
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	SBNO2 CNN2 POLR2E GPX4 RNU6-2 ARHGAP45 ABCA7 TMEM259

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding