Hs04024841_cn

• Gene Symbol: ARHGAP45
• Assay Reference Genome Location: Chr.19:1066410 on build GRCh38
• Cytoband: 19p13.3

Target Gene Details

• Entrez Gene ID: 23526
• Gene Name: Rho GTPase activating protein 45
• Gene Aliases: HA-1, HLA-HA1, HMHA1
• Location: Chr.19:1065923-1087831 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ARHGAP45	NM_001258328.2			NP_001245257.1
	AK300341.1
	DC382305.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1058677	Chr.19:1054061 - 1283189 on Build GRCh38	Loss	STK11 MIDN POLR2E LOC102725180 EFNA2 SBNO2 CBARP ARHGAP45 ATP5D CIRBP-AS1 GPX4 CIRBP C19orf24 ABCA7
nsv9662	Chr.19:893394 - 1317740 on Build GRCh38	Gain	STK11 RNU6-2 TMEM259 WDR18 ARID3A MIDN RNU6-9 POLR2E LOC102725180 EFNA2 CNN2 SBNO2 GRIN3B CBARP LOC105372235 ARHGAP45 ATP5D CIRBP-AS1 GPX4 KISS1R R3HDM4 CIRBP C19orf24 ABCA7
dgv136n111	Chr.19:1038223 - 1329640 on Build GRCh38	Deletion	STK11 MIDN POLR2E LOC102725180 EFNA2 CNN2 SBNO2 CBARP ARHGAP45 ATP5D CIRBP-AS1 GPX4 CIRBP C19orf24 ABCA7
nsv1160555	Chr.19:887275 - 1346084 on Build GRCh38	Deletion	RNU6-2 WDR18 MIDN POLR2E CBARP LOC105372235 ATP5D STK11 MED16 TMEM259 ARID3A RNU6-9 LOC102725180 EFNA2 CNN2 SBNO2 GRIN3B ARHGAP45 CIRBP-AS1 GPX4 KISS1R R3HDM4 CIRBP C19orf24 ABCA7
esv3643383	Chr.19:1012555 - 1069137 on Build GRCh38	Gain	RNU6-2 TMEM259 ARHGAP45 ABCA7 CNN2
nsv470102	Chr.19:1046521 - 1152656 on Build GRCh38	Loss	SBNO2 ARHGAP45 GPX4 POLR2E ABCA7
nsv469845	Chr.19:951640 - 1144486 on Build GRCh38	Loss	SBNO2 RNU6-2 TMEM259 GRIN3B WDR18 LOC105372235 ARID3A ARHGAP45 GPX4 POLR2E ABCA7 CNN2
nsv833704	Chr.19:951641 - 1144486 on Build GRCh38	Gain	SBNO2 RNU6-2 TMEM259 GRIN3B WDR18 LOC105372235 ARID3A ARHGAP45 GPX4 POLR2E ABCA7 CNN2
nsv953938	Chr.19:355801 - 1104501 on Build GRCh38	Deletion	GZMM RNU6-2 MADCAM1 WDR18 PLPPR3 RNF126 MIR3187 ODF3L2 POLR2E HCN2 MISP LOC105372235 CFD SHC2 MED16 TMEM259 THEG CDC34 ARID3A FSTL3 POLRMT FGF22 PRSS57 RNU6-9 CNN2 PRTN3 MIR4745 C2CD4C ELANE GRIN3B ARHGAP45 GPX4 PALM KISS1R R3HDM4 TPGS1 AZU1 LOC101928450 BSG ABCA7 PTBP1
dgv135n111	Chr.19:1014378 - 1156398 on Build GRCh38	Deletion	SBNO2 RNU6-2 TMEM259 ARHGAP45 GPX4 POLR2E ABCA7 CNN2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

intracellular signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

GTPase activator activity
protein binding
metal ion binding