Hs04084278_cn

• Gene Symbol: ISX
• Assay Reference Genome Location: Chr.22:35069670 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 91464
• Gene Name: intestine specific homeobox
• Gene Aliases: Pix-1, RAXLX
• Location: Chr.22:35066136-35087387 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ISX	NM_001303508.1			NP_001290437.1
	AB219123.1
	AK025181.1
	BC112212.1			AAI12213.1
	BC113633.1
	CR749372.1			CAH18225.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834182	Chr.22:34986155 - 35159250 on Build GRCh38	Gain	ISX-AS1 ISX LINC01399
nsv817989	Chr.22:35066656 - 35154238 on Build GRCh38	Loss	ISX LINC01399
nsv834183	Chr.22:35048670 - 35233532 on Build GRCh38	Gain	ISX LINC01399
esv35003	Chr.22:35060310 - 35175504 on Build GRCh38	Loss	ISX LINC01399
esv26909	Chr.22:35061958 - 35073684 on Build GRCh38	Gain	ISX
esv34121	Chr.22:34988871 - 35101201 on Build GRCh38	Loss	ISX-AS1 ISX
esv3647659	Chr.22:35064756 - 35171556 on Build GRCh38	Loss	ISX LINC01399
esv2661366	Chr.22:35064758 - 35171614 on Build GRCh38	Deletion	ISX LINC01399
esv2758835	Chr.22:35042419 - 35236960 on Build GRCh38	Loss	ISX LINC01399

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of vitamin A metabolic process
negative regulation of intestinal absorption

Function(s)

transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
sequence-specific DNA binding