Hs04226230_cn

• Gene Symbol: LOC102724965
• Assay Reference Genome Location: Chr.2:45651581 on build GRCh38
• Cytoband: 2p21

Target Gene Details

• Entrez Gene ID: 102724965
• Gene Name: collagen alpha-2(I) chain-like
• Gene Aliases: -
• Location: Chr.2:45648733-45652047 on Build GRCh38
• Assay Gene Location: Overlaps Intron 1 - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC102724965	XM_011533229.2			XP_011531531.2

Target Gene Details

• Entrez Gene ID: 5581
• Gene Name: protein kinase C epsilon
• Gene Aliases: PKCE, nPKC-epsilon
• Location: Chr.2:45651315-46187990 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PRKCE	XM_005264431.3	1	267	XP_005264488.1
	XM_017004492.1	1	267	XP_016859981.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv3804n100	Chr.2:45180603 - 45750333 on Build GRCh38	Gain	LOC102724965 PRKCE SRBD1 LINC01121
esv2751894	Chr.2:45141551 - 45772680 on Build GRCh38	Gain	LOC102724965 PRKCE SRBD1 LINC01121
nsv1013787	Chr.2:45541783 - 45738705 on Build GRCh38	Gain	LOC102724965 PRKCE SRBD1
dgv1119e212	Chr.2:45181796 - 45749281 on Build GRCh38	Gain	LOC102724965 PRKCE SRBD1 LINC01121
nsv998852	Chr.2:45419685 - 46135538 on Build GRCh38	Gain	LOC102724965 PRKCE SRBD1
nsv581741	Chr.2:45622938 - 45681498 on Build GRCh38	Gain	LOC102724965 PRKCE

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

macrophage activation involved in immune response
protein phosphorylation
apoptotic process
cell cycle
cell adhesion
signal transduction
activation of phospholipase C activity
positive regulation of epithelial cell migration
positive regulation of fibroblast migration
positive regulation of cell-substrate adhesion
peptidyl-serine phosphorylation
platelet activation
positive regulation of actin filament polymerization
negative regulation of protein ubiquitination
lipopolysaccharide-mediated signaling pathway
positive regulation of insulin secretion
positive regulation of synaptic transmission, GABAergic
positive regulation of cytokinesis
intracellular signal transduction
locomotory exploration behavior
TRAM-dependent toll-like receptor 4 signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to morphine
positive regulation of MAPK cascade
regulation of peptidyl-tyrosine phosphorylation
positive regulation of lipid catabolic process
release of sequestered calcium ion into cytosol
regulation of release of sequestered calcium ion into cytosol
cell division
regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of mucus secretion
cellular response to ethanol
cellular response to prostaglandin E stimulus
cellular response to hypoxia
positive regulation of wound healing
positive regulation of receptor activity
negative regulation of sodium ion transmembrane transporter activity
positive regulation of cellular glucuronidation

Function(s)

actin monomer binding
protein serine/threonine kinase activity
protein kinase C activity
calcium-independent protein kinase C activity
signal transducer activity
protein binding
ATP binding
enzyme activator activity
enzyme binding
receptor activator activity
ethanol binding
metal ion binding
14-3-3 protein binding