Hs04231586_cn

• Gene Symbol: UGT1A8
• Assay Reference Genome Location: Chr.2:233621626 on build GRCh38
• Cytoband: 2q37.1

Target Gene Details

• Entrez Gene ID: 54576
• Gene Name: UDP glucuronosyltransferase family 1 member A8
• Gene Aliases: UDPGT, UDPGT 1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H
• Location: Chr.2:233617645-233773299 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UGT1A8	NM_019076.4			NP_061949.3
	AF030310.1			AAB84259.1
	AF462267.1			AAL75963.1
	AF462268.1			AAL75964.1
	AK313488.1
	AY435143.1			AAR95644.1
	DQ364251.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2762307	Chr.2:233595877 - 233653333 on Build GRCh38	Gain	UGT1A8 UGT1A10
nsv584704	Chr.2:233618034 - 233660491 on Build GRCh38	Loss	UGT1A8 UGT1A10
nsv961572	Chr.2:233617748 - 233650941 on Build GRCh38	Duplication	UGT1A8 UGT1A10
esv2721664	Chr.2:233620664 - 233679344 on Build GRCh38	Deletion	UGT1A8 UGT1A9 UGT1A10
esv2721663	Chr.2:233617724 - 233636648 on Build GRCh38	Deletion	UGT1A8 UGT1A10
esv3893573	Chr.2:233595452 - 233639688 on Build GRCh38	Gain	UGT1A8 UGT1A10

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

glycosyltransferase

Gene Ontology Categories:

Process(es)

fatty acid metabolic process
steroid metabolic process
coumarin metabolic process
retinoic acid metabolic process
negative regulation of catalytic activity
negative regulation of fatty acid metabolic process
negative regulation of steroid metabolic process
flavone metabolic process
flavonoid glucuronidation
xenobiotic glucuronidation

Function(s)

retinoic acid binding
enzyme inhibitor activity
steroid binding
fatty acid binding
glucuronosyltransferase activity
protein homodimerization activity
protein heterodimerization activity