Hs04285086_cn

• Gene Symbol: SLBP
• Assay Reference Genome Location: Chr.4:1712283 on build GRCh38
• Cytoband: 4p16.3

Target Gene Details

• Entrez Gene ID: 7884
• Gene Name: stem-loop binding protein
• Gene Aliases: HBP
• Location: Chr.4:1692731-1712741 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLBP	NM_001306074.1	1	459	NP_001293003.1
	NM_001306075.1	1	459	NP_001293004.1
	NM_006527.3	1	459	NP_006518.1
	AK091735.1
	AK093314.1	1	66
	AK094257.1	1	273
	AK300826.1
	AK315635.1
	BC014908.1			AAH14908.1
	BC015703.1			AAH15703.1
	DB027411.1	1	66
	DB031118.1	1	66
	DC383752.1
	U75679.1			AAB97091.1
	Z71188.1			CAA94918.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428434	Chr.4:1623665 - 1813048 on Build GRCh38	Gain	LETM1 TACC3 SLBP TMEM129 FGFR3 FAM53A
nsv949756	Chr.4:1710274 - 1817773 on Build GRCh38	Deletion	LETM1 TACC3 SLBP TMEM129 FGFR3
dgv8901n54	Chr.4:1644637 - 1864631 on Build GRCh38	Loss	LETM1 TACC3 SLBP TMEM129 FGFR3 FAM53A
nsv593316	Chr.4:1526039 - 1768630 on Build GRCh38	Gain	TACC3 SLBP TMEM129 FAM53A
nsv508989	Chr.4:1623823 - 1846590 on Build GRCh38	Insertion	LETM1 TACC3 SLBP TMEM129 FGFR3 FAM53A
nsv1161027	Chr.4:1699833 - 1750693 on Build GRCh38	Deletion	TACC3 SLBP TMEM129
nsv470000	Chr.4:1522203 - 1722852 on Build GRCh38	Loss	TACC3 SLBP TMEM129 FAM53A

More Information

Additional Information:

For this assay, SNP(s) [rs181032842] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA metabolism protein

Gene Ontology Categories:

Process(es)

termination of RNA polymerase II transcription
mRNA 3'-end processing by stem-loop binding and cleavage
mRNA export from nucleus
histone mRNA metabolic process
nuclear DNA replication
mRNA transport

Function(s)

mRNA binding
protein binding
poly(A) RNA binding
histone pre-mRNA stem-loop binding
histone pre-mRNA DCP binding