Hs04371492_cn

• Gene Symbol: EXD3
• Assay Reference Genome Location: Chr.9:137345332 on build GRCh38
• Cytoband: 9q34.3

Target Gene Details

• Entrez Gene ID: 54932
• Gene Name: exonuclease 3'-5' domain containing 3
• Gene Aliases: mut-7
• Location: Chr.9:137306894-137423262 on Build GRCh38
• Assay Gene Location: Within Intron 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXD3	NM_017820.4			NP_060290.3
	XM_011518810.1			XP_011517112.1
	XM_011518814.1			XP_011517116.1
	XM_011518815.1			XP_011517117.1
	XM_017014861.1			XP_016870350.1
	XM_017014862.1			XP_016870351.1
	XM_017014863.1			XP_016870352.1
	XM_017014864.1			XP_016870353.1
	XM_017014865.1			XP_016870354.1
	XM_017014866.1			XP_016870355.1
	XM_017014867.1			XP_016870356.1
	AB061798.1			BAC10986.1
	AK055004.1			BAB70838.1
	AK091390.1
	AK094438.1			BAC04356.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv33008	Chr.9:137336337 - 137346333 on Build GRCh38	Loss	EXD3
dgv2190e212	Chr.9:137339864 - 137372892 on Build GRCh38	Gain	EXD3
nsv524322	Chr.9:136795692 - 137482216 on Build GRCh38	Loss	TPRN MIR4292 NDOR1 MIR3621 ANAPC2 TOR4A RNF224 CCDC183-AS1 PNPLA7 SLC34A3 PRR31 UAP1L1 TMEM210 CCDC183 MAMDC4 MIR7114 MAN1B1-AS1 C9orf173-AS1 LCN12 CLIC3 SSNA1 STPG3 PTGDS LRRC26 ENTPD8 TUBB4B RNF208 EDF1 LCNL1 ENTPD2 MIR4479 C9orf142 C8G FBXW5 RABL6 C9orf139 DPP7 TMEM203 GRIN1 C9orf172 TRAF2 SAPCD2 CYSRT1 NELFB EXD3 LOC101930307 NOXA1 FUT7 NSMF MAN1B1 ABCA2 NRARP NPDC1 FAM166A PHPT1
esv2759721	Chr.9:137303332 - 137447299 on Build GRCh38	Loss	EXD3 NOXA1 ENTPD8
nsv951207	Chr.9:137136949 - 137379148 on Build GRCh38	Deletion	NELFB EXD3 TPRN NDOR1 C9orf173-AS1 MIR3621 SSNA1 STPG3 NRARP ANAPC2 TOR4A LRRC26 RNF224 FAM166A TMEM203 SLC34A3 GRIN1 TUBB4B RNF208 CYSRT1 TMEM210
nsv1043075	Chr.9:137333691 - 137361369 on Build GRCh38	Gain+Loss	EXD3
nsv6770	Chr.9:137316337 - 137347440 on Build GRCh38	Insertion	EXD3
nsv1050826	Chr.9:137325391 - 137378611 on Build GRCh38	Gain	EXD3
nsv1161918	Chr.9:137118319 - 137438026 on Build GRCh38	Duplication	NELFB EXD3 NOXA1 TPRN NDOR1 C9orf173-AS1 MIR3621 SSNA1 STPG3 NRARP ANAPC2 TOR4A LRRC26 RNF224 ENTPD8 FAM166A TMEM203 SLC34A3 GRIN1 TUBB4B RNF208 CYSRT1 TMEM210
esv2422220	Chr.9:136584135 - 137350098 on Build GRCh38	Deletion	TPRN LINC01451 MIR4292 NDOR1 MIR3621 SNHG7 LOC100128593 SNORA17B AGPAT2 ANAPC2 TOR4A RNF224 CCDC183-AS1 SLC34A3 FAM69B MIR126 PRR31 UAP1L1 TMEM210 TMEM141 CCDC183 MAMDC4 LCN15 MAN1B1-AS1 C9orf173-AS1 LCN12 CLIC3 SSNA1 STPG3 PTGDS LRRC26 TUBB4B RNF208 EDF1 LCNL1 ENTPD2 MIR4479 C9orf142 C8G FBXW5 EGFL7 RABL6 C9orf139 DPP7 HSPC324 TMEM203 GRIN1 C9orf172 SNORA17A TRAF2 SAPCD2 CYSRT1 LCN10 NELFB EXD3 LOC101930307 FUT7 LCN6 MIR6722 MAN1B1 ABCA2 NRARP LCN8 NPDC1 FAM166A PHPT1
nsv1037407	Chr.9:137275904 - 137361369 on Build GRCh38	Gain	NRARP EXD3 TOR4A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

nucleic acid phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
3'-5' exonuclease activity
metal ion binding