Hs04439334_cn

• Gene Symbol: TDP1
• Assay Reference Genome Location: Chr.14:89964699 on build GRCh38
• Cytoband: 14q32.11

Target Gene Details

• Entrez Gene ID: 55775
• Gene Name: tyrosyl-DNA phosphodiesterase 1
• Gene Aliases: -
• Location: Chr.14:89954935-90044764 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TDP1	NM_001008744.1			NP_001008744.1
	NM_018319.3			NP_060789.2
	XM_005267847.2			XP_005267904.1
	XM_005267848.2			XP_005267905.1
	XM_006720197.3			XP_006720260.1
	XM_006720198.3			XP_006720261.1
	XM_006720199.1			XP_006720262.1
	XM_011536942.2			XP_011535244.1
	XM_011536943.2			XP_011535245.1
	XM_011536944.1			XP_011535246.1
	XM_017021439.1			XP_016876928.1
	XM_017021440.1			XP_016876929.1
	XM_017021441.1			XP_016876930.1
	XM_017021442.1			XP_016876931.1
	XM_017021443.1			XP_016876932.1
	XM_017021444.1			XP_016876933.1
	XM_017021445.1			XP_016876934.1
	XM_017021446.1			XP_016876935.1
	AF182002.1			AAF65623.1
	AK001952.1			BAA91997.1
	AK093235.1
	AK315549.1
	BC006083.1			AAH06083.1
	BC015474.1			AAH15474.1
	BC107877.1			AAI07878.1
	BX161451.1			CAD61915.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv832854	Chr.14:89877925 - 90070680 on Build GRCh38	Gain	EFCAB11 KCNK13 TDP1
nsv832853	Chr.14:89818942 - 89990332 on Build GRCh38	Gain	EFCAB11 TDP1
nsv1045864	Chr.14:89882005 - 89968468 on Build GRCh38	Loss	EFCAB11 TDP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

single strand break repair
DNA repair
double-strand break repair
nucleic acid phosphodiester bond hydrolysis

Function(s)

double-stranded DNA binding
single-stranded DNA binding
exonuclease activity
protein binding
3'-tyrosyl-DNA phosphodiesterase activity