Hs04475624_cn

• Gene Symbol: SERPINB4
• Assay Reference Genome Location: Chr.18:63639332 on build GRCh38
• Cytoband: 18q21.33

Target Gene Details

• Entrez Gene ID: 6318
• Gene Name: serpin family B member 4
• Gene Aliases: LEUPIN, PI11, SCCA-2, SCCA1, SCCA2
• Location: Chr.18:63637259-63644319 on Build GRCh38
• Assay Gene Location: Overlaps Intron 6 - Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SERPINB4	NM_002974.3			NP_002965.1
	NM_175041.1			NP_778206.1
	XM_011526138.1			XP_011524440.1
	AB046400.1			BAB40773.1
	AF461147.1			AAQ04771.1
	AK292212.1
	AY245780.1			AAO92271.1
	AY245782.1			AAO92273.1
	BC017401.1			AAH17401.1
	U19557.1			AAA97553.1
	X89015.1			CAA61420.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2313855	Chr.18:63635054 - 63653204 on Build GRCh38	Deletion	SERPINB4
nsv833672	Chr.18:63620445 - 63772481 on Build GRCh38	Gain	SERPINB11 SERPINB7 SERPINB4 SERPINB3
nsv1066552	Chr.18:63147299 - 64608176 on Build GRCh38	Gain	SERPINB11 HMSD LINC01538 SERPINB7 SERPINB2 SERPINB12 SERPINB3 SERPINB10 SERPINB13 BCL2 KDSR LINC00305 SERPINB4 LOC284294 VPS4B SERPINB8 SERPINB5
dgv621e214	Chr.18:63635738 - 63656397 on Build GRCh38	Loss	SERPINB4 SERPINB3
dgv994e212	Chr.18:63635616 - 63653554 on Build GRCh38	Loss	SERPINB4

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of peptidase activity
negative regulation of endopeptidase activity
regulation of proteolysis
protection from natural killer cell mediated cytotoxicity

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
enzyme binding