Hs04650436_cn

• Gene Symbol: BCL2L11
• Assay Reference Genome Location: Chr.2:111121095 on build GRCh38
• Cytoband: 2q13

Target Gene Details

• Entrez Gene ID: 10018
• Gene Name: BCL2 like 11
• Gene Aliases: BAM, BIM, BOD
• Location: Chr.2:111120914-111168445 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BCL2L11	NM_001204106.1	1	182	NP_001191035.1
	NM_001204107.1	1	182	NP_001191036.1
	NM_001204108.1	1	182	NP_001191037.1
	NM_001204109.1	1	182	NP_001191038.1
	NM_001204110.1	1	182	NP_001191039.1
	NM_001204111.1	1	182	NP_001191040.1
	NM_001204112.1	1	182	NP_001191041.1
	NM_001204113.1	1	182	NP_001191042.1
	NM_006538.4	1	182	NP_006529.1
	NM_138621.4	1	182	NP_619527.1
	NM_138622.3	1	182	NP_619528.1
	NM_138623.3	1	182	NP_619529.1
	NM_138624.3	1	182	NP_619530.1
	NM_138625.3	1	182	NP_619531.1
	NM_138626.3	1	182	NP_619532.1
	NM_138627.3	1	182	NP_619533.1
	NM_207002.3	1	182	NP_996885.1
	NM_207003.2	1	182	NP_996886.1
	XM_005263556.3	1	182	XP_005263613.1
	XM_005263561.3	1	182	XP_005263618.1
	XM_017003102.1	1	182	XP_016858591.1
	AK290377.1	1	182
	AK291269.1	1	182
	BC033694.1	1	167	AAH33694.1
	CN411912.1	1	152

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829618	Chr.2:111118050 - 111123970 on Build GRCh38	Gain	BCL2L11 ACOXL
nsv582699	Chr.2:110763166 - 112172487 on Build GRCh38	Loss	BCL2L11 ACOXL LOC400997 MIR4435-2HG TMEM87B ANAPC1 MIR4435-2 FBLN7 MERTK MIR4771-2 PAFAH1B1P2
nsv521956	Chr.2:110634682 - 112341235 on Build GRCh38	Loss	BCL2L11 BUB1 LOC400997 MIR4435-2HG TMEM87B ZC3H8 ZC3H6 MIR4771-2 PAFAH1B1P2 ACOXL SNORD132 ANAPC1 MIR4435-2 FBLN7 MERTK
nsv834331	Chr.2:111054562 - 111247101 on Build GRCh38	Loss	BCL2L11 ACOXL LOC400997 MIR4435-2HG
dgv4047n100	Chr.2:110308696 - 112358403 on Build GRCh38	Loss	BCL2L11 BUB1 RGPD6 LOC400997 MIR4435-2HG TMEM87B ZC3H8 ZC3H6 MIR4771-2 PAFAH1B1P2 LOC105375809 ACOXL LOC105373553 LOC100288570 SNORD132 ANAPC1 LINC01106 MIR4435-2 LIMS4 FBLN7 MERTK

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

in utero embryonic development
B cell homeostasis
B cell apoptotic process
kidney development
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
myeloid cell homeostasis
apoptotic process
meiosis I
cell-matrix adhesion
spermatogenesis
brain development
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
mammary gland development
positive regulation of protein homooligomerization
response to endoplasmic reticulum stress
tube formation
odontogenesis of dentin-containing tooth
T cell homeostasis
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of neuron apoptotic process
ear development
positive regulation of cell cycle
regulation of organ growth
developmental pigmentation
regulation of developmental pigmentation
spleen development
thymus development
post-embryonic organ morphogenesis
positive regulation of apoptotic process by virus
cellular process regulating host cell cycle in response to virus
thymocyte apoptotic process
positive regulation of release of cytochrome c from mitochondria
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
apoptotic process involved in embryonic digit morphogenesis
positive regulation of IRE1-mediated unfolded protein response
positive regulation of fibroblast apoptotic process
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
microtubule binding
dynein binding