Hs04693427_cn

• Gene Symbol: ATF2
• Assay Reference Genome Location: Chr.2:175073636 on build GRCh38
• Cytoband: 2q31.1

Target Gene Details

• Entrez Gene ID: 1386
• Gene Name: activating transcription factor 2
• Gene Aliases: CRE-BP1, CREB-2, CREB2, HB16, TREB7
• Location: Chr.2:175072250-175168206 on Build GRCh38
• Assay Gene Location: Within Exon 17

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ATF2	NM_001256090.1	15	2825	NP_001243019.1
	NM_001256091.1	14	2750	NP_001243020.1
	NM_001256092.1	13	2693	NP_001243021.1
	NM_001256093.1	13	2725	NP_001243022.1
	NM_001880.3	14	2790	NP_001871.2
	NR_045768.1	17	2987
	NR_045769.1	17	3019
	NR_045770.1	16	2872
	NR_045771.1	15	2864
	NR_045772.1	15	2802
	NR_045773.1	14	2767
	NR_045774.1	13	2675
	AF283776.2	1	411
	AK128731.1
	AL050192.1	1	403
	BC107698.1	13	2660	AAI07699.1
	BX648469.1	13	2580

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3575313	Chr.2:174591458 - 175085724 on Build GRCh38	Gain	ATF2 CHN1 CHRNA1 H3F3AP4 LOC105373750 WIPF1
nsv1012709	Chr.2:175023400 - 175840083 on Build GRCh38	Gain	ATF2 MIR933 ATP5G3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

basic leucine zipper transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
outflow tract morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to osmotic stress
cellular response to DNA damage stimulus
response to water deprivation
histone acetylation
intra-S DNA damage checkpoint
positive regulation of transforming growth factor beta2 production
positive regulation of neuron apoptotic process
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of epithelial cell proliferation
regulation of sequence-specific DNA binding transcription factor activity
positive regulation of sequence-specific DNA binding transcription factor activity
adipose tissue development
amelogenesis
positive regulation of mitochondrial membrane permeability involved in apoptotic process

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
enhancer sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
cAMP response element binding protein binding
protein kinase binding
cAMP response element binding
metal ion binding
protein heterodimerization activity