Hs04707894_cn

• Gene Symbol: AMER3
• Assay Reference Genome Location: Chr.2:130767226 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 205147
• Gene Name: APC membrane recruitment protein 3
• Gene Aliases: FAM123C
• Location: Chr.2:130754475-130768134 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMER3	NM_001105193.1	2	5328	NP_001098663.1
	NM_001105194.1	2	5264	NP_001098664.1
	NM_001105195.1	2	5261	NP_001098665.1
	NM_152698.2	2	5344	NP_689911.2
	XM_011510793.2	2	6370	XP_011509095.1

Target Gene Details

• Entrez Gene ID: 653269
• Gene Name: POTE ankyrin domain family member I
• Gene Aliases: POTE2beta
• Location: Chr.2:130462245-131626428 on Build GRCh38
• Assay Gene Location:

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POTEI

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4074n100	Chr.2:130550793 - 131291209 on Build GRCh38	Gain	FAM168B POTEJ TISP43 POTEI LOC440910 AMER3 POTEE CFC1 CYP4F30P ARHGEF4 PLEKHB2 GPR148
dgv731e199	Chr.2:130678437 - 131300107 on Build GRCh38	Deletion	FAM168B POTEI LOC440910 AMER3 POTEE CYP4F30P ARHGEF4 PLEKHB2 GPR148
esv2670824	Chr.2:130625264 - 131605218 on Build GRCh38	Deletion	MZT2A CCDC74A NOC2LP2 LOC440910 AMER3 MIR4784 POTEE POTEKP CYP4F30P ARHGEF4 PLEKHB2 TUBA3D WTH3DI FAM168B LINC01120 POTEJ LOC150776 POTEI GPR148
esv3893337	Chr.2:130722838 - 131194387 on Build GRCh38	Loss	FAM168B POTEI AMER3 ARHGEF4 PLEKHB2 GPR148
dgv616e201	Chr.2:130674635 - 131312550 on Build GRCh38	Deletion	FAM168B POTEI LOC440910 AMER3 POTEE CYP4F30P ARHGEF4 PLEKHB2 GPR148
nsv583136	Chr.2:130730100 - 130846832 on Build GRCh38	Loss	POTEI AMER3 ARHGEF4 GPR148
nsv1014723	Chr.2:130720375 - 131379551 on Build GRCh38	Loss	WTH3DI FAM168B POTEI LOC440910 AMER3 POTEE ARHGEF4 PLEKHB2 GPR148
nsv583135	Chr.2:130724905 - 131194388 on Build GRCh38	Loss	FAM168B POTEI AMER3 ARHGEF4 PLEKHB2 GPR148
nsv524021	Chr.2:130724906 - 131553515 on Build GRCh38	Loss	MZT2A CCDC74A NOC2LP2 LOC440910 AMER3 MIR4784 POTEE ARHGEF4 PLEKHB2 TUBA3D WTH3DI FAM168B LINC01120 LOC150776 POTEI GPR148
esv2760576	Chr.2:130634172 - 131521752 on Build GRCh38	Gain+Loss	MZT2A NOC2LP2 LOC440910 AMER3 MIR4784 POTEE CYP4F30P ARHGEF4 PLEKHB2 TUBA3D WTH3DI FAM168B LINC01120 POTEJ LOC150776 POTEI GPR148
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	LOC389033 CFC1B LOC440910 LOC101927924 POTEF GPR39 CYP4F62P FAM201B LINC01120 POTEI RAB6C CCDC74B LINC01087 FAR2P1 C2orf27B NOC2LP2 AMER3 POTEE CFC1 POTEKP CYP4F30P ARHGEF4 PLEKHB2 TUBA3D TUBA3E LOC150776 MED15P9 GPR148 CCDC74A C2orf27A WTH3DI ZNF806 POTEJ PTPN18 TISP43 MZT2B LOC100507460 RAB6C-AS1 LOC107985778 MZT2A IMP4 CCDC115 NOC2LP1 LOC646743 MIR4784 MIR663B SMPD4 FAM168B FAR2P2 ANKRD30BL
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	LOC389033 CFC1B LOC101927924 POTEF CYP4F62P POTEJ PTPN18 TISP43 MZT2B POTEI RAB6C CCDC74B RAB6C-AS1 FAR2P1 LOC107985778 IMP4 CCDC115 NOC2LP1 LOC646743 AMER3 CFC1 CYP4F30P ARHGEF4 SMPD4 TUBA3E FAR2P2 MED15P9 GPR148

More Information

• Set Membership: Intragenic, Exonic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

Wnt signaling pathway
anatomical structure development
regulation of canonical Wnt signaling pathway

Function(s)

protein binding
phosphatidylinositol-4,5-bisphosphate binding
beta-catenin binding