Hs04730301_cn

• Gene Symbol: LOC105376997
• Assay Reference Genome Location: Chr.3:25384118 on build GRCh38
• Cytoband: 3p24.2

Target Gene Details

• Entrez Gene ID: 105376997
• Gene Name: uncharacterized LOC105376997
• Gene Aliases: -
• Location: Chr.3:25383105-25384927 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LOC105376997	NR_134933.1
	AK131021.1
	AW273730.1
	BX098796.1

Target Gene Details

• Entrez Gene ID: 5915
• Gene Name: retinoic acid receptor beta
• Gene Aliases: HAP, MCOPS12, NR1B2, RARbeta1, RRB2
• Location: Chr.3:24829323-25597932 on Build GRCh38
• Assay Gene Location: Within Intron 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RARB	NM_001290216.2			NP_001277145.1
	NM_001290300.1			NP_001277229.1
	AK299756.1
	DC376623.1
	DQ083391.1			AAZ32403.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3893676	Chr.3:24984204 - 26577498 on Build GRCh38	Loss	LINC00692 LOC105376997 MIR4442 NGLY1 TOP2B RARB OXSM
nsv834645	Chr.3:25322232 - 25513616 on Build GRCh38	Gain	LOC105376997 RARB

More Information

Additional Information:

For this assay, SNP(s) [rs78963521] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

C4 zinc finger nuclear receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
ureteric bud development
glandular epithelial cell development
outflow tract septum morphogenesis
retinal pigment epithelium development
growth plate cartilage development
transcription initiation from RNA polymerase II promoter
signal transduction
positive regulation of cell proliferation
negative regulation of cell proliferation
striatum development
regulation of myelination
negative regulation of chondrocyte differentiation
embryonic hindlimb morphogenesis
multicellular organism growth
positive regulation of apoptotic process
negative regulation of apoptotic process
steroid hormone mediated signaling pathway
positive regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic eye morphogenesis
retinoic acid receptor signaling pathway
embryonic digestive tract development
ventricular cardiac muscle cell differentiation

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
steroid hormone receptor activity
retinoic acid receptor activity
drug binding
zinc ion binding
protein complex binding
retinoid X receptor binding