Hs04758506_cn

• Gene Symbol: UBE2E1
• Assay Reference Genome Location: Chr.3:23820479 on build GRCh38
• Cytoband: 3p24.2

Target Gene Details

• Entrez Gene ID: 7324
• Gene Name: ubiquitin conjugating enzyme E2 E1
• Gene Aliases: UBCH6
• Location: Chr.3:23805893-23891640 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
UBE2E1	NM_001202476.1			NP_001189405.1
	NM_003341.4			NP_003332.1
	NM_182666.2			NP_872607.1
	XM_005265431.4			XP_005265488.1
	AK295354.1
	AK314854.1
	BC009139.1			AAH09139.1
	BF698653.1
	BI223271.1
	DB478686.1
	DB499676.1
	X92963.1			CAA63539.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv834637	Chr.3:23662437 - 23844653 on Build GRCh38	Loss	UBE2E1-AS1 UBE2E1
nsv1005186	Chr.3:21989661 - 24089392 on Build GRCh38	Gain	UBE2E2 ZNF385D RPL15 UBE2E2-AS1 UBE2E1-AS1 UBE2E1 NR1D2 NKIRAS1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

protein polyubiquitination
ubiquitin-dependent protein catabolic process
histone monoubiquitination
protein ubiquitination
anaphase-promoting complex-dependent catabolic process
ISG15-protein conjugation
histone H2B ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
protein K48-linked ubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ATP binding
ISG15 transferase activity
ubiquitin conjugating enzyme activity